Efgartigimod Alfa Injection – 400mg – Low price wholesale comparison
$0.80
Efgartigimod Alfa Injection delivers 400mg of efgartigimod in 5.6ml pre-filled vial. Subcutaneous formulation approved under SJ20240029. Manufactured by Patheon Italia S.p.A. For research use only.
?Please consult staff for price, other specifications and uses?
描述
Efgartigimod alfa is a neonatal Fc receptor (FcRn) antagonist, designed to reduce pathogenic IgG antibody levels. It’s widely researched in autoimmune disorders, such as myasthenia gravis, immune thrombocytopenia (ITP), and pemphigus vulgaris.
This subcutaneous injectable formulation contains 400mg of efgartigimod in a 5.6ml solution. Manufactured by Patheon Italia S.p.A., and approved in China under NMPA SJ20240029 with product code 86984816000020.
?? For laboratory research only. Not for clinical, diagnostic, or veterinary use.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Efgartigimod Alfa Injection (Subcutaneous) |
| Generic Name | Efgartigimod Alfa |
| CAS Number | 2269744-99-4 |
| Molecular Class | Human IgG1-derived Fc fragment antibody |
| Formulation | Injection (subcutaneous) |
| Strength | 400mg/5.6ml |
| Dosage Form | Pre-filled vial |
| Approval Number | SJ20240029 (China NMPA) |
| Product Code | 86984816000020 |
| Manufacturer | Patheon Italia S.p.A. |
| Packaging | 1 vial per box |
| Intended Use | For laboratory research only |
| Storage Conditions | 2–8°C; protect from light, do not freeze |
Mechanism & Research Applications
Efgartigimod alfa binds to neonatal Fc receptor (FcRn), interfering with IgG recycling. This leads to increased degradation of circulating pathogenic IgG antibodies — a novel therapeutic mechanism in autoimmune disease research.
Common Research Areas:
-
Myasthenia gravis models
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Pemphigus and ITP immunopathology
-
FcRn-mediated IgG homeostasis
-
IgG turnover and half-life studies
-
Fc fusion protein therapeutics
Side Effects (Observed in Research Models)
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Mild injection site reactions
-
Transient headache or fatigue
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Increased risk of infections under prolonged exposure
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Transient leukopenia in rodent models
-
Gastrointestinal disturbances in higher dosing
Ensure all use complies with animal ethics and safety standards.
Safety & Handling
-
Use Restriction: Laboratory research use only
-
PPE: Gloves, lab coat, goggles required
-
Storage: Refrigerate (2–8°C), do not freeze
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Disposal: Follow chemical and biological waste protocols
Core Keywords
Efgartigimod Alfa injection, FcRn blocker research, 400mg efgartigimod vial, autoimmune IgG inhibitor, Patheon Italia biologics, NMPA SJ20240029, lab-grade efgartigimod, wholesale research antibody modulators
Research Use Disclaimer
This product is for experimental research use only. Not for use in humans or animals. Misuse may lead to regulatory or health risks. Always follow institutional biosafety procedures.
其他信息
| 重量 | 1 公斤 |
|---|---|
| 尺寸 | 32 × 36 × 32 厘米 |
A1: No. This product is strictly for non-clinical laboratory research.
A2: No. It is not approved for therapeutic or diagnostic purposes.
A3: Yes, available upon request for all institutional orders.
A4: Yes. Wholesale and retail options are available globally.
A5: Efgartigimod alfa is engineered to specifically bind FcRn with high affinity, enabling selective IgG clearance without affecting other immunoglobulins.
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