Description

Eledoisin is an undecapeptide derived from molluscan sources and structurally related to Substance P. It binds neurokinin receptors (NK1, NK2, NK3), triggering responses such as vasodilation, increased capillary permeability, smooth muscle contraction (e.g. bladder, gut), and modulation of gastric acid secretion depending on dose. These bioactivities make it a valuable research tool in neuropharmacology, smooth muscle physiology, and receptor signaling studies.

Product Specifications

Mechanism of Action & Research Applications

Eledoisin mimics tachykinin peptides by activating NK1, NK2, and NK3 receptors with high potency (pD? values ranging ~7–9) . It activates intracellular signaling cascades such as phospholipase C and calcium mobilization, leading to physiological responses like smooth muscle contraction and vasodilation. These properties make it ideal for mechanistic studies of receptor pharmacology, cardiovascular physiology, gastrointestinal motility, and neurochemical signaling models.

Side Effects (For Reference Only)

Eledoisin is for laboratory use only—its effects in humans are not established. In animal and in vitro studies, notable actions include vasodilation and smooth muscle modulation. Always use appropriate lab safety procedures when handling.

Disclaimer

This product is strictly for laboratory research purposes. It is not approved for diagnostic or therapeutic use in humans or animals. Please follow institutional safety protocols when handling.