描述
Entecavir is a potent nucleoside reverse transcriptase inhibitor (NRTI) effective against hepatitis B virus (HBV). These tablets are suitable for pharmacological and virology research involving antiviral efficacy, resistance mechanisms, and pharmacokinetics in hepatocyte models. The 0.5?mg strength aligns with standard dosing in chronic HBV studies.
Entecavir Tablets Product Specifications
Parameter | Details |
---|---|
Product Name | Entecavir Tablets (Renhe) |
Generic Name | Entecavir |
CAS Number | 142217?69?4 |
Molecular Formula | C??H??N?O? |
Molecular Weight | ~277.28?g/mol |
Dosage Form | Oral tablet |
Strength | 0.5?mg per tablet |
Pack Size | 14 tablets ×?2 blisters = 28 tablets per bottle |
NMPA Approval No. | H20213196 |
Drug Standard Code | 86905388003431 |
Manufacturer | Jiangxi Pharmaceutical Co., Ltd. |
Barcode | 6903919183458 |
Storage Conditions | Store <?25?°C, sealed, protect from moisture and light |
Intended Use | For laboratory and preclinical HBV antiviral research |
Entecavir Tablets Mechanism of Action
Entecavir acts as a guanosine analogue that inhibits HBV reverse transcriptase, preventing viral DNA synthesis in infected cells. It offers high antiviral potency with minimal resistance, making it a valuable compound in chronic HBV research.
Entecavir Tablets Research Application Areas
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Chronic hepatitis B viral suppression studies
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Antiviral resistance and mutation modeling
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Pharmacokinetic and bioavailability analysis
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Combination therapy with other antivirals (e.g. tenofovir, lamivudine)
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In vitro hepatocyte and in vivo animal studies
Safety & Handling
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Handling: Use standard lab PPE—gloves, coat, goggles; avoid ingestion.
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Storage: Maintain below 25?°C, sealed and dry.
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Precautions: Designed for laboratory use only; not for human or veterinary administration.
Core Keywords
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Research Use Disclaimer
This product is for laboratory and preclinical research use only. It is not approved for clinical, therapeutic, diagnostic, or veterinary applications. Misuse may carry legal or health risks. Use under approved institutional protocols.
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