Description

Etoricoxib is a selective cyclooxygenase-2 (COX-2) inhibitor, classified under nonsteroidal anti-inflammatory drugs (NSAIDs). It is used in preclinical and pharmacodynamic research to model inflammation, osteoarthritis, rheumatoid arthritis, and acute pain. Etoricoxib exhibits a targeted action by sparing COX-1 and selectively inhibiting COX-2, making it ideal for comparative studies with other NSAIDs.

This 60?mg strength is suitable for dose-response assays and chronic administration research.

Etoricoxib Tablets Product Specifications

Etoricoxib Tablets Mechanism of Action

Etoricoxib selectively inhibits COX-2 enzymes, which are responsible for the synthesis of prostaglandins involved in inflammation, swelling, and pain. It does not significantly affect COX-1, preserving gastrointestinal protection and platelet function. This mechanism is suitable for studying:

• Anti-inflammatory mechanisms

• Pain signaling pathways

• NSAID-induced side effects

• Arthritis progression in animal models

Etoricoxib Tablets Research Applications

• Rheumatoid arthritis and osteoarthritis models

• Acute and chronic inflammation studies

• Pain modulation and analgesic testing

• Comparative research with non-selective NSAIDs

• COX-2 inhibitor pharmacokinetics

Etoricoxib Tablets Side Effects (Observed in Lab Settings)

• Gastrointestinal discomfort (low incidence vs traditional NSAIDs)

• Elevated liver enzymes in long-term studies

• Cardiovascular effects at high doses

• Renal function fluctuations

• Headache or dizziness in animal subjects

Safety & Handling

• Use appropriate lab PPE (gloves, goggles, lab coat)

• Avoid inhalation and contact with eyes or skin

• Handle in a well-ventilated lab setting

• Not for use in humans or animals

• Dispose of according to institutional safety regulations

Core Keywords

Etoricoxib tablets, CAS 202409-33-4, COX-2 inhibitor, Hainitan etoricoxib, NSAID for lab research, anti-inflammatory model drug, etoricoxib 60mg research, osteoarthritis inflammation research, lab-grade etoricoxib, etoricoxib for pain models

Research Use Disclaimer

This product is intended strictly for laboratory research. It is not approved for therapeutic, diagnostic, or veterinary use. Handle only in certified facilities by trained research professionals.