Exemestane Factory wholesale price
$1.00
Exemestane (brand: Yunitan®) is a potent, irreversible steroidal aromatase inhibitor used in preclinical studies of postmenopausal, estrogen receptor-positive breast cancer and hormone-dependent tumor models. Supplied as 250?mg capsules in a 30-count box. Manufactured by Hainan General Alliance Pharm. Co., Ltd. and registered under China NMPA approval H20020011 (product code?86905822000330).
?? For laboratory research use only.?Please consult the staff for other purposes?
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Exemestane Capsules (Yunitan®) |
| Generic Name | Exemestane |
| CAS Number | 107868?30?4 : |
| Molecular Formula | C??H??O? |
| Molecular Weight | 296.41?g/mol |
| Dosage Form | Oral capsule |
| Strength | 0.25?g (250?mg) per capsule |
| Pack Size | 30 capsules per box |
| Approval Number | H20020011 (China NMPA) |
| Product Code | 86905822000330 |
| Manufacturer | Hainan General Alliance Pharmaceutical Co., Ltd. |
| Storage | Store at 20?25?°C, protect from moisture |
| Intended Use | Laboratory research only |
Mechanism of Action
Exemestane is a steroidal, irreversible (“suicide”) inhibitor of aromatase, converting into a reactive intermediate that permanently inactivates the enzyme, effectively suppressing estrogen synthesis labeling.pfizer.com+15zh.wikipedia.org+15pubchem.ncbi.nlm.nih.gov+15.
Research Applications & Pharmacology
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Commonly used in preclinical breast cancer models and hormone-dependent tumor studies
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Potent inhibition: IC?? ? 30–40?nM in human placental and rat ovarian aromatase
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Pharmacokinetics: Oral bioavailability ~60%, protein binding ~90%, half-life ~24?h; excreted half in urine, half in feces
Safety Profile & Side Effects
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Frequently observed: joint pain, hot flashes, fatigue, headache, nausea, mood changes, elevated liver enzymes
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Lab safety: Use PPE, monitor endocrine markers and bone parameters in animal models
?? Research?Use Disclaimer
This product is exclusively for laboratory research use. It is not approved for clinical, diagnostic, therapeutic, or veterinary use. Misuse may pose health risks and compromise scientific validity.
其他信息
| 重量 | 1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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