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Felodipine Extended-Release Tablets (Jiangbo) 5mg – For Laboratory Research Use Only
$1.00
Felodipine Extended-Release Tablets (Jiangbo) contain 5mg of felodipine per tablet, with 18 tablets per box. Manufactured by Laiyang Jiangbo Pharmaceutical Co., Ltd. For laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?
Description
Felodipine is a long-acting calcium channel blocker widely studied in laboratory research for its vasodilatory effects on the cardiovascular system. As an L-type calcium channel inhibitor, felodipine reduces vascular resistance and is a valuable tool in hypertension and pharmacokinetic modeling studies.
This product is supplied in a dosage of 5mg per extended-release tablet, with 2 blister packs of 9 tablets each (18 tablets total) per box.
Manufactured by Laiyang Jiangbo Pharmaceutical Co., Ltd., this product is NMPA approved (H20103190) and is intended exclusively for laboratory research use.
?? For laboratory research use only. Not for human or veterinary use.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Felodipine Extended-Release Tablets (Jiangbo) |
| Generic Name | Felodipine |
| CAS Number | 72509-76-3 |
| Molecular Formula | C18H19Cl2NO4 |
| Molecular Weight | 384.25 g/mol |
| Dosage Form | Extended-Release Tablet |
| Strength | 5mg per tablet |
| Packaging | 9 tablets × 2 blisters per box |
| Approval Number | H20103190 (China NMPA) |
| Product Code | 86903995000102 |
| Manufacturer | Laiyang Jiangbo Pharmaceutical Co., Ltd. |
| Barcode | 6975307140343 |
| Intended Use | Laboratory research only |
| Storage Conditions | Store sealed, in a cool, dry place below 25°C |
Mechanism of Action & Research Applications
Felodipine works by selectively inhibiting voltage-gated L-type calcium channels in vascular smooth muscle. This action reduces calcium influx, causing vasodilation, decreased peripheral resistance, and lower arterial pressure—without significantly affecting heart rate or myocardial contractility.
Common Research Uses:
Hypertension pharmacology studies
Calcium signaling and vascular tone models
Extended-release pharmacokinetics
Comparative research on dihydropyridine calcium antagonists
Cardiovascular and endothelial research
Side Effects (Observed in Research Models)
In experimental applications, felodipine may demonstrate:
Dose-dependent hypotension
Peripheral edema
Reflex tachycardia
Gastrointestinal disturbances (rare)
Safety & Handling
Use Restriction: For research use only. Not for human or veterinary applications.
Personal Protective Equipment (PPE): Gloves, lab coat, and safety goggles recommended.
Disposal: Comply with institutional protocols for hazardous waste disposal.
Research Use Disclaimer
This product is strictly for laboratory research use. Not intended for human, veterinary, clinical, or diagnostic applications. Misuse may result in regulatory and health risks.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 23 × 26 × 23 cm |
Q1: Is this product approved for therapeutic use?
A1: No. It is strictly intended for laboratory research and not approved for clinical use.
Q2: Can this be purchased in bulk?
A2: Yes. We support both wholesale and retail orders. Please inquire for volume discounts.
Q3: Is documentation like COA and SDS available?
A3: Yes. Certificate of Analysis (COA) and Safety Data Sheet (SDS) are available upon request.
Q4: What research areas benefit most from felodipine?
A4: Felodipine is ideal for cardiovascular studies, arterial stiffness models, hypertension research, and drug absorption kinetics.
Q5: What’s the significance of extended-release formulation?
A5: It allows sustained plasma concentrations in experimental models, enabling accurate pharmacokinetic studies over time.
Q6: How does felodipine differ from amlodipine in lab models?
A6: Felodipine has a shorter half-life and more vascular selectivity, useful for isolated vasodilation studies.
Q7: Can felodipine be used in combination with beta-blockers in research?
A7: Yes, it’s often studied in combination with beta-blockers to assess synergistic cardiovascular effects.
Q8: Does felodipine affect heart rate in animal studies?
A8: In some models, reflex tachycardia may occur due to vasodilation, though less pronounced than in earlier CCBs.
Q9: Is felodipine soluble in water for in vitro use?
A9: No. Felodipine has poor water solubility and typically requires DMSO or ethanol for dissolution.
Q10: What are common control compounds used with felodipine in studies?
A10: Amlodipine, nifedipine, and verapamil are often used as reference calcium channel blockers in comparative experiments.
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