描述
Felypressin Acetate (also referred to as PLV-2 acetate) is a potent, non-catecholamine vasoconstrictor and selective agonist of the vasopressin V1a receptor. It is widely utilized in dental pharmacology and cardiovascular research due to its strong vasopressor effect, comparable to epinephrine but without activating adrenergic pathways. Felypressin enhances diastolic blood pressure effectively and is considered safer for hypertensive subjects when used appropriately.
Synthesized under GMP-compliant conditions with at least 99.60% purity, this product ensures consistency and reliability in experimental protocols involving vascular tone modulation, signal transduction, and cardiovascular responses.
Product Specifications
Parameter | Details |
---|---|
Product Name | Felypressin Acetate |
Synonyms | PLV-2 Acetate; 2-Phenylalanine-8-Lysine Vasopressin Acetate |
CAS No. | 914453-97-7 |
Purity | ? 99.60% |
Molecular Formula | C??H??N??O??S?•xC?H?O? |
Molecular Weight | ~1100.28 Da |
Appearance | White to off-white powder |
Solubility | Soluble in DMSO; slight solubility in water and methanol |
Storage Conditions | Store at –20 °C; protect from light and moisture; solutions stable up to 6 months at –80 °C |
Manufacturing Standard | GMP-compliant |
Applications | Cardiovascular research, anesthesia models, GPCR/V1a pathway studies |
Regulatory Status | For laboratory research use only |
Mechanism of Action & Research Applications
Felypressin Acetate acts selectively on vasopressin V1a receptors, inducing vasoconstriction of vascular smooth muscle cells with effects comparable to epinephrine—but without adrenergic stimulation. Its potent vasopressor action is especially utilized in dental research, cardiovascular physiology studies, and investigations of GPCR-mediated signal transduction. Animal studies demonstrate its ability to boost diastolic pressure while causing minimal cardiac side effects.
Side Effects (For Reference Only)
Felypressin Acetate is for experimental use only and lacks comprehensive clinical safety data. Reported effects in animal studies include bradycardia associated with elevated arterial pressure. Use appropriate lab safety procedures during handling.
Disclaimer
This product is strictly for laboratory research. It is not approved for human or veterinary use. Please comply with your institution’s safety protocols.
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