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Felypressin Acetate (CAS 914453-97-7) – GMP Manufacturer
$2.00
Felypressin Acetate is a synthetic vasopressin V1a receptor agonist (purity ? 99.60%), manufactured under GMP standards. It provides potent vasoconstrictive effects without catecholamine activity, making it valuable for research in cardiovascular pharmacology and anesthesia models. Suitable for both wholesale and retail; strictly for laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?
Description
Felypressin Acetate (also referred to as PLV-2 acetate) is a potent, non-catecholamine vasoconstrictor and selective agonist of the vasopressin V1a receptor. It is widely utilized in dental pharmacology and cardiovascular research due to its strong vasopressor effect, comparable to epinephrine but without activating adrenergic pathways. Felypressin enhances diastolic blood pressure effectively and is considered safer for hypertensive subjects when used appropriately.
Synthesized under GMP-compliant conditions with at least 99.60% purity, this product ensures consistency and reliability in experimental protocols involving vascular tone modulation, signal transduction, and cardiovascular responses.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Felypressin Acetate |
| Synonyms | PLV-2 Acetate; 2-Phenylalanine-8-Lysine Vasopressin Acetate |
| CAS No. | 914453-97-7 |
| Purity | ? 99.60% |
| Molecular Formula | C??H??N??O??S?•xC?H?O? |
| Molecular Weight | ~1100.28 Da |
| Appearance | White to off-white powder |
| Solubility | Soluble in DMSO; slight solubility in water and methanol |
| Storage Conditions | Store at –20 °C; protect from light and moisture; solutions stable up to 6 months at –80 °C |
| Manufacturing Standard | GMP-compliant |
| Applications | Cardiovascular research, anesthesia models, GPCR/V1a pathway studies |
| Regulatory Status | For laboratory research use only |
Mechanism of Action & Research Applications
Felypressin Acetate acts selectively on vasopressin V1a receptors, inducing vasoconstriction of vascular smooth muscle cells with effects comparable to epinephrine—but without adrenergic stimulation. Its potent vasopressor action is especially utilized in dental research, cardiovascular physiology studies, and investigations of GPCR-mediated signal transduction. Animal studies demonstrate its ability to boost diastolic pressure while causing minimal cardiac side effects.
Side Effects (For Reference Only)
Felypressin Acetate is for experimental use only and lacks comprehensive clinical safety data. Reported effects in animal studies include bradycardia associated with elevated arterial pressure. Use appropriate lab safety procedures during handling.
Disclaimer
This product is strictly for laboratory research. It is not approved for human or veterinary use. Please comply with your institution’s safety protocols.
Additional information
| Weight | 0.5 kg |
|---|---|
| Dimensions | 26 × 23 × 26 cm |
What is Felypressin Acetate used for in research?
Felypressin Acetate is primarily used in cardiovascular and anesthesia models to study vasoconstriction and GPCR-mediated V1a receptor activation.
What is the purity of this product?
This GMP-grade product is provided with a high purity of at least 99.60%.
How does Felypressin Acetate act biologically?
It selectively binds to V1a receptors on vascular smooth muscle cells, inducing potent vasoconstriction similar to epinephrine but without adrenergic stimulation
What are common applications for Felypressin Acetate?
It is used in research involving cardiovascular physiology, dental anesthetic models, and signal transduction via vasopressin receptors
How soluble is Felypressin Acetate and how should I store it?
It is soluble in DMSO and slightly soluble in water and methanol. Store it at –20 °C, protect from moisture and light; prepared solutions remain stable up to 6 months at –80 °C
Can Felypressin Acetate be used clinically?
No—this product is strictly for laboratory research and not approved for clinical use.
Is bulk purchasing available?
Yes, Felypressin Acetate is available in both wholesale and retail quantities, complete with GMP documentation.
What is the molecular weight of Felypressin Acetate?
Its molecular weight is approximately 1100.28 Da
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