Flumazenil 1?mg / 10?mL Vial Wholesale price comparison
$2.00
Flumazenil is a selective GABA? benzodiazepine receptor antagonist primarily used to reverse benzodiazepine-induced sedation in preclinical research. Supplied as a 10?mL vial containing 1?mg (0.1?mg/mL).
?? For laboratory research use only?Please consult staff for other specifications and uses?
描述
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Flumazenil Injection |
| Generic Name | Flumazenil (Ethyl 8?fluoro?5?methyl?6?oxo?5,6?dihydro?4H?imidazo[1,5?a][1,4]benzodiazepine?3?carboxylate) |
| CAS Number | 78755?81?4 |
| Molecular Formula | C??H??FN?O? |
| Molecular Weight | 303.29?g/mol |
| Dosage Form | Sterile injectable solution (IV use) |
| Strength | 0.1?mg/mL (1?mg per 10?mL vial) |
| Pack Size | 1 vial per box |
| Approval Number | H20243371 (China NMPA) |
| Product Code | 86983450000045 |
| Manufacturer | Sichuan Meidakang Jiale Pharmaceutical Co., Ltd. |
| Storage | Store at controlled room temperature; protect from light |
| Intended Use | Laboratory research only |
Mechanism of Action
Flumazenil competitively binds at the benzodiazepine recognition site on GABA? receptors, reversing the sedative and CNS?depressant effects of benzodiazepines gutnliver.org+15pubchem.ncbi.nlm.nih.gov+15en.wikipedia.org+15.
Research Applications & Pharmacology
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Sedation reversal models: Useful in controlled reversal of benzodiazepine-induced CNS depression in animal studies pdf.hres.ca+12ncbi.nlm.nih.gov+12en.wikipedia.org+12.
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Pharmacokinetics:
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Onset in 1–2 minutes; peak effect at 6–10 minutes; duration ~19–50 minutes depending on dose and benzodiazepine type .
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Eliminated primarily by the liver; terminal half-life ~40–80 minutes; excretion is ~90–95% renal, ~5–10% fecal .
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Safety Profile & Handling
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Adverse events: Possible seizures, resedation, transient anxiety, nausea; caution in benzodiazepine-dependent models .
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Contraindications (in research): Avoid in subjects predisposed to seizure, with co-administration of TCA, or prolonged benzodiazepine exposure .
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Handling tips: Administer slowly IV (2?mL per 15?s); monitor neuromotor and respiratory function; have emergency protocols ready .
?? Research?Use Disclaimer
This product is intended solely for laboratory research use. It is not approved for therapeutic, diagnostic, clinical, or veterinary applications. Misuse may pose significant risks and affect experimental integrity.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
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