Flumazenil Injection 0.5?mgLow price wholesale

Flumazenil Injection 0.5?mgLow price wholesale

$3.00

Flumazenil Injection (brand: Henan Runhong) is supplied as sterile lyophilized powder in vials containing 0.5?mg active flumazenil per 5?mL. Approved under NMPA H20254517. A selective GABA_A benzodiazepine receptor antagonist—ideal for laboratory research in sedation reversal, receptor binding assays, neuropharmacology, and overdose models.?? Strictly for laboratory research use only.?Please consult staff for other specifications and uses?

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Description

Product Specifications

SpecificationDescription
Product NameFlumazenil Injection (Henan Runhong)
Generic NameFlumazenil
CAS Number78755?81?4
Molecular FormulaC??H??FN?O?
Molecular Weight~303.29?g/mol
FormulationLyophilized sterile powder for injection, reconstitute with sterile diluent
Strength0.5?mg per 5?mL vial
Pack Size1 vial per box (additional info by request)
Approval NumberH20254517 (NMPA, China)
ManufacturerHenan Runhong Pharmaceutical Co., Ltd.
Storage ConditionsStore at 2–8?°C; protect from light and moisture
Intended UseFor laboratory research only

Mechanism of Action

Flumazenil is a competitive antagonist at the benzodiazepine binding site of the GABA_A receptor complex, reversing sedative, hypnotic, and amnestic effects of benzodiazepine and “Z?drug” agonists


Research Applications & Pharmacology

  • Sedation reversal models: Ideal for studies on benzodiazepine overdose and anesthesia recovery .

  • Receptor binding assays: Used to probe benzodiazepine site interactions via radiolabeled or functional displacement assays .

  • Pharmacokinetics & metabolism: Rapid onset (1–2?min), distribution half-life ~4–11?min, terminal 40–80?min; mainly hepatic metabolism with urinary excretion (~90?95%)

  • Withdrawal & tolerance studies: Used to precipitate acute withdrawal in long-term benzodiazepine models


Safety Profile & Handling

  • Preclinical side effects: In animal models, abrupt reversal can trigger convulsions, anxiety, and withdrawal seizures

  • Handling: Use PPE; reconstitute under sterile conditions; visually inspect before use.

  • Storage & disposal: Follow institutional biosafety and chemical waste protocols.


Core Keywords

flumazenil injection, benzodiazepine receptor antagonist, CAS?78755?81?4, sedation reversal research, GABA_A antagonist, overdose model reagent, Henan Runhong flumazenil


Research?Use Disclaimer

This product is intended exclusively for laboratory research purposes. It is not approved for clinical, therapeutic, diagnostic, or veterinary applications. Misuse may pose serious health risks. Users must comply with institutional safety guidelines.

Additional information

Weight1 kg
Dimensions28 × 26 × 28 cm

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