描述
Galantamine hydrobromide is a reversible acetylcholinesterase inhibitor with nicotinic receptor potentiating effects, first derived from plants like Galanthus. It’s used in research targeting neuromuscular disorders, cognitive impairment, and reversal of neuromuscular blockade.
Jialaimin is supplied as a 1?mg/ml solution in 1?ml ampoules, with 10 ampoules per box. It is manufactured by Suicheng Pharmaceutical Co., Ltd. and authorized under NMPA registration H41023666, product code 86903204000213, barcode 6923671409283.
?? For laboratory research use only. Not for clinical, veterinary, or diagnostic applications.
Product Specifications
Parameter | Details |
---|---|
Product Name | Galantamine Hydrobromide Injection (Jialaimin) |
Generic Name | Galantamine Hydrobromide |
CAS Number | 1953?04?4 |
Molecular Formula | C??H??NO?·HBr |
Molecular Weight | ??368.27?g/mol |
Dosage Form | Injectable solution in ampoules |
Strength | 1?mg per 1?ml ampoule |
Packaging | 10 ampoules per box |
Approval Number | H41023666 (China NMPA) |
Product Code | 86903204000213 |
Manufacturer | Suicheng Pharmaceutical Co., Ltd. |
Barcode | 6923671409283 |
Intended Use | Laboratory research only |
Storage Conditions | Protect from light, store sealed (2–25?°C) |
Mechanism & Research Applications
Galantamine acts as a reversible acetylcholinesterase (AChE) inhibitor and allosteric potentiator of nicotinic acetylcholine receptors, which increases synaptic acetylcholine levels and enhances cholinergic transmission.
Typical research areas include:
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Reversal of neuromuscular blockade (e.g., curare)
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Experimental models of myasthenia gravis, post-polio syndrome, and neuromuscular impairment
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Cognitive function and Alzheimer’s disease models
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Neuropharmacology of cholinergic and nicotinic systems
Side Effects (Observed in Research Models)
In preclinical use, potential effects include:
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Transient bradycardia
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Cholinergic symptoms (salivation, GI discomfort)
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Allergic reactions (rare)
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Nicotinic overstimulation symptoms
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Reversal of neuromuscular blockade with cholinergic effects
Researchers should incorporate proper monitoring protocols and dosing guidelines.
Safety & Handling
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Use Restriction: For laboratory research use only.
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PPE: Gloves, lab coat, and eyewear required.
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Storage: Maintain sealed ampoules in a cool, light-protected environment (2–25?°C).
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Disposal: Follow biosafety and chemical waste disposal regulations.
Core Keywords
Galantamine hydrobromide injection, Jialaimin galantamine, H41023666 injection, neuromuscular blockade reversal agent, AChE inhibitor injection, cholinergic research ampoules, lab-grade galantamine injection, wholesale galantamine hydrobromide
Research Use Disclaimer
This product is exclusively for laboratory use in research settings. It is not approved for clinical, veterinary, diagnostic, or therapeutic purposes. Misuse may carry regulatory and health risks. Always follow institutional biosafety procedures and local regulations.
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