描述
Gemcitabine Hydrochloride Injection Product Specifications
Attribute | Details |
---|---|
Product Name | Gemcitabine Hydrochloride Injection |
Strength | 200?mg per vial (0.2?g) |
Quantity | 8 vials per box |
Dosage Form | Lyophilized injectable powder |
CAS Number | 122111?03?9 |
Molecular Formula | C?H??F?N?O?·HCl |
Molecular Weight | ~299.7?g/mol |
Approval No. | China NMPA H20093568 |
Product Code | 86906932000029 |
Barcode | 6948677980024 |
Manufacturer | Hainan Jinrui Pharmaceutical Co., Ltd. |
Intended Use | Laboratory research use only — Not for human or veterinary use |
Mechanism of Action
Gemcitabine (dFdC) acts as a nucleoside analogue that halts DNA replication by two mechanisms: inhibition of ribonucleotide reductase via dFdCDP and incorporation into DNA as dFdCTP, inducing apoptosis.
Research Applications
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Cancer cell line studies: pancreatic, lung, bladder, breast, and ovarian models
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DNA synthesis inhibition and replication stress assays
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Combined therapy testing (with cisplatin, paclitaxel, targeted agents)
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Formulation research (e.g., nanoparticles, liposomal delivery systems)
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Pharmacokinetics, cytotoxicity, and efficacy profiling
?? Research?Use Disclaimer
This product is provided strictly for laboratory research and development use only. Not intended for human, veterinary, clinical, diagnostic, or therapeutic use.
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