Description
Introduction
The GLP-1/GIP/glucagon combination therapy represents a breakthrough in metabolic medicine, offering superior weight loss and glycemic control compared to single-agonist drugs. As a trusted wholesale supplier of peptide therapeutics, we provide high-purity GLP-1, GIP, and glucagon receptor agonists at factory-direct prices for clinics, researchers, and distributors.
This comprehensive guide covers:
Science behind triple-agonist therapy
Key benefits for obesity & diabetes
Wholesale pricing vs. retail costs
How to source premium-quality peptides
Product Specifications: GLP-1/GIP/Glucagon Combination Peptides
| Parameter | Details |
|---|---|
| Active Components | Liraglutide (GLP-1), Tirzepatide (GIP/GLP-1), Retatrutide (GLP-1/GIP/Glucagon) |
| Purity | 98% (HPLC-verified) |
| Form | Lyophilized powder |
| Solubility | Reconstitutes in bacteriostatic water |
| Storage | 2-8°C (lyophilized), -20°C long-term |
| Shelf Life | 24 months |
| Packaging | 2mg, 5mg, 10mg vials (bulk discounts available) |
Quality Assurance:
Third-party tested for purity, sterility, and endotoxins
GMP-certified manufacturing
Batch-specific COAs provided
How GLP-1/GIP/Glucagon Combination Therapy Works
1. Triple-Agonist Mechanism
Unlike single-target drugs (e.g., Semaglutide), this approach activates three metabolic pathways:
| Receptor | Primary Effects |
|---|---|
| GLP-1 | ? Insulin secretion, glucagon, slows gastric emptying |
| GIP | Enhances GLP-1 effects, improves fat metabolism |
| Glucagon | Increases energy expenditure via fat oxidation |
2. Clinical Advantages Over Single-Agonist Drugs
24%+ body weight loss (vs. 15% with Semaglutide) (Source: NEJM Retatrutide Trial)
Faster HbA1c reduction in type 2 diabetes
Improved lipid profile (lowers triglycerides, raises HDL

Key Applications & Benefits
1. Obesity Treatment (Superior to Wegovy®/Mounjaro®)
Appetite suppression: Targets brain hunger centers more effectively
Metabolic boost: Glucagon increases calorie burning
Less muscle loss: Preserves lean mass better than GLP-1 alone
2. Type 2 Diabetes Management
Dual glucose control: GLP-1 + GIP synergistically lower blood sugar
Cardioprotective effects: Reduces heart disease risk factors
3. Emerging Uses
NAFLD/NASH treatment: Reduces liver fat accumulation
Neuroprotection: Potential cognitive benefits in Alzheimer’s research
Wholesale Pricing vs. Retail Comparison
Retail Cost (FDA-Approved Brands)
| Drug | Monthly Price (With Insurance) | Cash Price |
|---|---|---|
| Wegovy® (GLP-1) | $900–$1,300 | $1,400+ |
| Mounjaro® (GLP-1/GIP) | $1,000–$1,500 | $1,600+ |
| Retatrutide* (Future) | Estimated $1,200–$1,800 | $1,800+ |
*Not yet FDA-approved (2024 projection)
Wholesale Lyophilized Powder Pricing
| Quantity | Price per 5mg Vial | Savings vs. Retail |
|---|---|---|
| 1–10 vials | $XXX.XX | ~60% less |
| 10–50 vials | $XXX.XX | ~75% less |
| 50+ vials | Custom bulk pricing | Up to 85% savings |
Why Buy Wholesale?
Avoid insurance restrictions
Ideal for compounding pharmacies
Higher profit margins for resellers
How to Use GLP-1/GIP/Glucagon Peptides
Reconstitution Guide
Add 1–2mL bacteriostatic water to lyophilized powder
Gently swirl (don’t shake) until clear
Store reconstituted solution at 2-8°C for ?30 days
Dosing Protocol
Weight loss: Start at 0.5mg/week, titrate to 2–5mg/week
Diabetes: 0.25mg initial dose, increase to 1–2mg weekly
Always consult a healthcare provider for personalized dosing
Why Source From Us?
Direct GMP-certified factory connection
Batch-specific third-party testing
Bulk discounts (up to 40% off retail)
Discreet global shipping
Limited Offer: Free shipping on orders >50 vials








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