描述
Introduction
The GLP-1/GIP/glucagon combination therapy represents a breakthrough in metabolic medicine, offering superior weight loss and glycemic control compared to single-agonist drugs. As a trusted wholesale supplier of peptide therapeutics, we provide high-purity GLP-1, GIP, and glucagon receptor agonists at factory-direct prices for clinics, researchers, and distributors.
This comprehensive guide covers:
? Science behind triple-agonist therapy
? Key benefits for obesity & diabetes
? Wholesale pricing vs. retail costs
? How to source premium-quality peptides
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Product Specifications: GLP-1/GIP/Glucagon Combination Peptides
Parameter | Details |
---|---|
Active Components | Liraglutide (GLP-1), Tirzepatide (GIP/GLP-1), Retatrutide (GLP-1/GIP/Glucagon) |
Purity | ?98% (HPLC-verified) |
Form | Lyophilized powder |
Solubility | Reconstitutes in bacteriostatic water |
Storage | 2-8°C (lyophilized), -20°C long-term |
Shelf Life | 24 months |
Packaging | 2mg, 5mg, 10mg vials (bulk discounts available) |
? Quality Assurance:
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Third-party tested for purity, sterility, and endotoxins
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GMP-certified manufacturing
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Batch-specific COAs provided
How GLP-1/GIP/Glucagon Combination Therapy Works
1. Triple-Agonist Mechanism
Unlike single-target drugs (e.g., Semaglutide), this approach activates three metabolic pathways:
Receptor | Primary Effects |
---|---|
GLP-1 | ? Insulin secretion, ? glucagon, slows gastric emptying |
GIP | Enhances GLP-1 effects, improves fat metabolism |
Glucagon | Increases energy expenditure via fat oxidation |
2. Clinical Advantages Over Single-Agonist Drugs
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24%+ body weight loss (vs. 15% with Semaglutide) (Source: NEJM Retatrutide Trial)
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Faster HbA1c reduction in type 2 diabetes
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Improved lipid profile (lowers triglycerides, raises HDL
Key Applications & Benefits
1. Obesity Treatment (Superior to Wegovy®/Mounjaro®)
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Appetite suppression: Targets brain hunger centers more effectively
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Metabolic boost: Glucagon increases calorie burning
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Less muscle loss: Preserves lean mass better than GLP-1 alone
2. Type 2 Diabetes Management
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Dual glucose control: GLP-1 + GIP synergistically lower blood sugar
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Cardioprotective effects: Reduces heart disease risk factors
3. Emerging Uses
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NAFLD/NASH treatment: Reduces liver fat accumulation
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Neuroprotection: Potential cognitive benefits in Alzheimer’s research
Wholesale Pricing vs. Retail Comparison
Retail Cost (FDA-Approved Brands)
Drug | Monthly Price (With Insurance) | Cash Price |
---|---|---|
Wegovy® (GLP-1) | $900–$1,300 | $1,400+ |
Mounjaro® (GLP-1/GIP) | $1,000–$1,500 | $1,600+ |
Retatrutide* (Future) | Estimated $1,200–$1,800 | $1,800+ |
*Not yet FDA-approved (2024 projection)
Wholesale Lyophilized Powder Pricing
Quantity | Price per 5mg Vial | Savings vs. Retail |
---|---|---|
1–10 vials | $XXX.XX | ~60% less |
10–50 vials | $XXX.XX | ~75% less |
50+ vials | Custom bulk pricing | Up to 85% savings |
? Why Buy Wholesale?
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Avoid insurance restrictions
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Ideal for compounding pharmacies
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Higher profit margins for resellers
How to Use GLP-1/GIP/Glucagon Peptides
Reconstitution Guide
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Add 1–2mL bacteriostatic water to lyophilized powder
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Gently swirl (don’t shake) until clear
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Store reconstituted solution at 2-8°C for ?30 days
Dosing Protocol
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Weight loss: Start at 0.5mg/week, titrate to 2–5mg/week
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Diabetes: 0.25mg initial dose, increase to 1–2mg weekly
Always consult a healthcare provider for personalized dosing
Why Source From Us?
? Direct GMP-certified factory connection
? Batch-specific third-party testing
? Bulk discounts (up to 40% off retail)
? Discreet global shipping
? Limited Offer: Free shipping on orders >50 vials
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