Description

Hydroxychloroquine sulfate is a 4-aminoquinoline compound widely used in autoimmune disease and malaria research. It exhibits immunomodulatory and antimalarial activity, making it a valuable compound for cellular studies, inflammation models, and viral inhibition assays.

The Nitimei formulation offers 0.2g per tablet, with 10 tablets per box, manufactured by Grandpharma (China) Co., Ltd., approved by China NMPA under the registration number H20243521, with product code 86983383000082 and barcode 6901592403047.

?? This product is intended strictly for laboratory research use only. It is not for clinical or diagnostic applications.

Product Specifications

Mechanism & Research Applications

Hydroxychloroquine sulfate acts by:

• Raising the pH of intracellular vacuoles, interfering with lysosomal activity

• Inhibiting antigen presentation and cytokine production

• Modulating TLR signaling and endosomal fusion

• Being explored in inflammation, viral infection, and autoimmune disease models

Research applications include:

• Systemic lupus erythematosus (SLE) cellular models

• Malaria parasite inhibition assays

• Antiviral drug comparative studies

• Rheumatoid arthritis cytokine studies

• COVID-19 mechanism-related screening (in vitro)

Side Effects (Observed in Research Models)

Reported adverse effects in research environments:

• Retinal cell cytotoxicity (in dose-dependent studies)

• Cardiotoxicity in long-term high-exposure models

• Gastrointestinal cell irritation

• Neuromuscular weakness in animal testing

• Elevated liver enzymes under repeated use

Researchers must apply proper dosing protocols and monitoring.

Safety & Handling

• Use Restriction: For laboratory research only. Not for human or veterinary use

• PPE: Gloves, safety goggles, and lab coat required during handling

• Storage: Store below 25°C in dry, sealed conditions

• Disposal: Comply with local and institutional chemical disposal procedures

Core Keywords

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Research Use Disclaimer

This product is supplied exclusively for laboratory research. It is not approved for human, veterinary, or diagnostic use. Improper handling or misuse may result in legal or health risks. Follow your institution’s biosafety and chemical handling standards.