Description

Indocyanine green (ICG) is a water-soluble, near-infrared fluorescent dye used to assess cardiac output, liver function, and tissue perfusion. After intravenous reconstitution, ICG binds tightly to plasma proteins and is exclusively removed via biliary excretion, making it ideal for dynamic clearance studies and angiographic research. Its strong fluorescence at ~800?nm supports imaging in vascular, gastrointestinal, and hepatic research models.

Product Specifications

Mechanism of Action

Indocyanine Green fluoresces in the near?infrared range (~800?nm) upon intravenous injection. It binds strongly to plasma proteins (~98%), remains in the vascular compartment, and is rapidly cleared exclusively by hepatic uptake and biliary excretion. This pharmacokinetic profile makes it a reliable indicator for dynamic liver and circulation studies.

Research Application Areas

• Hepatic clearance and function assays

• Cardiac output and blood flow measurement

• Vascular and tissue perfusion imaging

• Near?infrared fluorescence angiography models

• Preclinical imaging in liver and oncology research

Safety & Handling

• Preparation: Reconstitute powder with sterile water or saline; use within 6 hours.

• Handling: Use lab PPE, avoid aerosolization or contact.

• Storage: Keep unopened vial at 20–25?°C; shield from moisture and light.

• Precautions: Dye contains sodium iodide; monitor for hypersensitivity in experimental models.

Core Keywords

indocyanine green injection, ICG 25mg vial, CAS 3599?32?4, H20055881, near-infrared dye, liver function research, cardiac output indicator, fluorescence imaging dye wholesale

Research Use Disclaimer

This product is strictly for laboratory research and preclinical imaging. Not approved for clinical, diagnostic, therapeutic, or veterinary use. Misuse may pose legal or health risks. Use only under institutional oversight and approved research protocols.