描述
Isepamicin Sulfate Injection Product Specifications
Parameter | Details |
---|---|
Product Name | Isepamicin Sulfate Injection (Hongsheng) |
Generic Name | Isepamicin Sulfate |
Synonyms | Isepacin, Asepacin, 6?-(Hydroxyaminomethyl)-Amikacin |
CAS Number | — (refer to PubChem Isepamicin Sulfate, CID?3037209) |
Formulation | Injectable solution |
Strength | 0.2?g / 2?mL per vial |
Pack Size | 10 vials per box |
Dosage Form | IV/IM injection (for research use) |
Approval Number | NMPA China: H20084625 |
Product Code | 86904645000060 |
Manufacturer | Zhejiang Hongsheng Pharmaceutical Co., Ltd. |
Barcode | Not assigned — contact pharmacist |
Description | Clear, colorless solution |
Storage | Room temperature, away from light |
Intended Use | Laboratory research only |
Mechanism of Action
Isepamicin is an aminoglycoside antibiotic that binds to the 30S bacterial ribosomal subunit, disrupting protein synthesis. It retains activity against many aminoglycoside-resistant gram?negative bacteria hongshengyy.com+8pubchem.ncbi.nlm.nih.gov+8synapse.patsnap.com+8.
Research Applications & Pharmacology
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Studies of respiratory, urinary, bloodstream, wound, and abdominal infections caused by gram-negative organisms
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Investigation of aminoglycoside resistance mechanisms, nephrotoxicity, and ototoxicity
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Dosing in vitro/in vivo models: Adults typically receive 400?mg/day divided doses by IV/IM during preclinical translation
Safety Profile & Handling
Adverse Reactions (Preclinical data):
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Nephrotoxicity (kidney damage) and ototoxicity (hearing loss, tinnitus)
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Other effects: rash, neuromuscular weakness, GI upset, hematologic changes, injection-site pain
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Contraindicated in renal failure or known aminoglycoside hypersensitivity (or family history)
Handling Instructions:
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Use full lab PPE: gloves, coat, goggles
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Administer via IV infusion over ?30?min (or IM) as per research protocol
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Monitor renal/hearing function in animal models
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Dispose compliant with biosafety standards
?? Research Use Disclaimer
This product is intended only for laboratory research. Not for therapeutic, clinical, diagnostic, or veterinary use. Improper use may lead to serious health risks and regulatory non-compliance.
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