Description

Isosorbide Dinitrate Injection (Isoket) is a nitrate-based vasodilator compound, primarily utilized in laboratory settings to study cardiovascular function, vascular smooth muscle behavior, and nitric oxide signaling pathways.

Each ampoule contains 10mg of isosorbide dinitrate in a 10ml solution. It is widely used in preclinical experiments involving coronary dilation, myocardial ischemia modeling, and vascular reactivity assays.

Manufactured by Ever Pharma Jena GmbH (Germany) and approved in China under NMPA registration HJ20160408, product code 86978851000930.

?? For research use only. Not for therapeutic, diagnostic, or veterinary applications.

Product Specifications

Mechanism & Research Applications

Isosorbide dinitrate is a nitrate ester that undergoes enzymatic conversion to nitric oxide (NO), resulting in vascular smooth muscle relaxation. It is extensively used in research for:

• Investigating vasodilation and blood pressure regulation

• Studying myocardial oxygen supply-demand balance

• Developing models for angina pectoris and heart failure

• Research on nitric oxide donors and cGMP signaling

• Evaluating vascular resistance and endothelial function

Its action on both venous and arterial systems makes it a key tool in cardiovascular research studies.

Safety & Handling

• Use Restriction: For research purposes only. Not for human or veterinary administration.

• Protective Equipment: Wear gloves, goggles, and lab coat when handling.

• Storage Instructions: Store sealed under 25°C; avoid light and excessive humidity.

• Disposal: Follow institutional protocols for chemical and pharmaceutical waste.

Research Use Disclaimer

This product is intended exclusively for laboratory research purposes. It is not certified for use in humans or animals. Improper use may result in safety or legal consequences. Always follow national regulations and laboratory biosafety guidelines.