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Lidocaine & Prilocaine Cream 30?g ×?10 Tubes [For Laboratory Research Use Only]
$1.00
This topical cream combines 2.5% lidocaine and 2.5% prilocaine, offering local anesthesia before minor dermatological procedures, injections, or catheter insertions. Marketed as Jinsaining®, it provides rapid dermal analgesia when applied with occlusive dressing. Each box includes ten 30?g tubes.
?? For experimental laboratory work only. ?Please consult the staff for other purposes?
Description
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Lidocaine & Prilocaine Cream (Jinsaining®) |
| Active Ingredients | Lidocaine 2.5% + Prilocaine 2.5% |
| CAS Number | 101362?25?8 (Lidocaine/Prilocaine eutectic mix) mayoclinic.org+5en.wikipedia.org+5trial.medpath.com+5mayoclinic.org+2dailymed.nlm.nih.gov+2drugs.com+2synapse.patsnap.com+1en.wikipedia.org+1 |
| Molecular Formula | C27H42N4O2 (combined) |
| Dosage Form | Emulsion cream |
| Strength | 2.5% Lidocaine + 2.5% Prilocaine (each tube) |
| Pack Size | 30?g ×?10 tubes |
| Approval Number | H20233629 (NMPA, China) |
| Product Code | 86983354000011 |
| Manufacturer | Ruyuan Dongyangguang Pharmaceutical Co., Ltd. |
| Barcode | 6976155270060 |
| Storage | Store at 15–25?°C, protect from heat |
| Intended Use | Research-use topical local anesthetic only |
Mechanism of Action
Lidocaine and prilocaine are amide-type local anesthetics that block voltage-gated sodium channels in nerve membranes, preventing action potential initiation and propagation. The eutectic mixture allows effective skin penetration due to its low melting point.
Research Applications
Experimental dermatology: Used to numb skin before minor procedures (venipuncture, biopsies, laser therapy) in animal or human skin models .
Onset & duration: Analgesia begins ~60 minutes after application and lasts 1–2 hours post-removal; mucosal application acts faster (5–10 min) .
Pharmacokinetics:
Lidocaine: ~70% plasma protein binding, t½ ~1.5–2 h
Prilocaine: 55% protein binding, t½ ~10–150 min
Safety Profile & Handling
Adverse Events (preclinical/human data):
Local: transient blanching, erythema, edema, rash
Systemic (rare): dizziness, headache, methemoglobinemia in infants (<0.5%)
Handling Tips:
Apply a thick layer under occlusion for 1 hour (>2 hours for deeper analgesia)
Avoid broken skin or mucosa to reduce absorption risk
Use PPE; dispose as pharmaceutical waste
?? Research?Use Disclaimer
This product is intended strictly for experimental laboratory use. It is not approved nor intended for therapeutic, diagnostic, clinical, or veterinary use. Misuse may compromise safety and data validity.
Additional information
| Weight | 1.1 kg |
|---|---|
| Dimensions | 18 × 16 × 18 cm |
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