描述
Product Specifications
Attribute | Details |
---|---|
Product Name | Lornoxicam Injection (Harasanlian®) |
Generic Name | Lornoxicam (Chlortenoxicam) |
CAS Number | 70374?39?9 caymanchem.com+1targetmol.com+1 |
Molecular Formula | C??H??ClN?O?S? |
Molecular Weight | ~371.8?g/mol |
Dosage Form | Solution for IV/IM Injection |
Strength | 8?mg per ampoule |
Pack Size | 6 ampoules per box |
Approval Number | H20057160 (China NMPA) |
Product Code | 86903662001906 |
Manufacturer | Harbin Sanlian Pharmaceutical Co., Ltd. |
Storage | Store at 2–8?°C, protect from light |
Intended Use | Laboratory research use only |
Mechanism of Action
Lornoxicam non-selectively inhibits COX-1 and COX-2, reducing prostaglandin synthesis to alleviate inflammation, pain, and fever. Notably, it has a relatively short elimination half-life (3–5?hrs), potentially leading to improved tolerability sciencedirect.com+15pubmed.ncbi.nlm.nih.gov+15link.springer.com+15.
Research Applications & Pharmacology
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Acute & postoperative pain models: Injection (4–8?mg) provides analgesia comparable to morphine or tramadol.
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Inflammatory disease studies: Effective in arthritis, osteoarthritis, and ankylosing spondylitis models.
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Renal colic and musculoskeletal pain: Rapid VAS reduction, effective within 30 minutes.
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Pharmacokinetics: Rapid absorption, high protein binding, hepatic metabolism to 5??hydroxy?lornoxicam, excreted via urine/feces.
Safety Profile & Handling
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Adverse events: Mostly mild GI disturbances; rare serious effects like bleeding or bronchospasm.
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Administration risk: Monitor for hypotension and renal function during studies.
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Handling: Use PPE; reconstitute under sterile conditions; dispose of as pharmaceutical waste.
?? Research?Use Disclaimer
This product is designed exclusively for laboratory research. It is not approved for therapeutic, diagnostic, clinical, or veterinary applications. Misuse may present health risks and compromise experimental integrity.
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