Description

Lornoxicam is an oxicam-type nonsteroidal anti-inflammatory drug (NSAID) with potent analgesic, anti-inflammatory, and antipyretic effects. It functions by inhibiting both COX?1 and COX?2 enzymes, reducing prostaglandin synthesis without escalating leukotriene formation.

The Jinshukang/Jinruikang freeze-dried injection delivers approximately 8.6?mg of lornoxicam in an 8?mg labeled vial. It is manufactured by Hainan Jinrui Pharmaceutical Co., Ltd., approved under China NMPA number H20133241, national drug code 86979280000225, barcode 6947589810184.

? Specifically for preclinical use in inflammation, pain, arthritis, and enzymatic assays where injectable NSAID formulations are preferred. Not approved for human or veterinary use.

Lornoxicam Injection Product Specifications

Mechanism & Research Applications

Lornoxicam inhibits cyclooxygenase enzymes COX?1 and COX?2, effectively reducing prostaglandin-mediated inflammation and pain. Unique among similar drugs, it does not shift metabolism toward leukotrienes .

Common research applications include:

• In vitro/in vivo inflammation and pain models (e.g., rheumatoid arthritis, osteoarthritis)

• Analgesic efficacy testing

• Enzymatic assays of COX pathway

• Comparative studies with other NSAIDs

• Investigating side effect profiles and mechanisms of action

Clinical studies show 8?mg IV/IM doses provide effective pain relief with good tolerability.

Lornoxicam Injection Side Effects (Research Context)

Laboratory and clinical data highlight the following potential adverse effects:

• GI irritation or bleeding (nausea, abdominal pain)

• Headache, dizziness, sedation

• Rare serious reactions: bronchospasm, hypersensitivity, or skin rash

• Cardiovascular and renal caution similar to other NSAIDs

Use suitable monitoring protocols for animal models and cell cultures.

Safety & Handling

• Use Restriction: For laboratory research only; not approved for human/veterinary use

• Handling: Use sterile technique and standard lab PPE (gloves, lab coat, safety glasses)

• Storage: Store sealed between 2–8?°C; avoid freezing and direct light

• Disposal: Follow institutional chemical waste policies

Core Keywords

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Research Use Disclaimer

This product is exclusively for laboratory research use and not approved for clinical, therapeutic, diagnostic, or veterinary use. Misuse may carry safety and regulatory risks. Always adhere to institutional biosafety and handling guidelines.