Lorutengitide | CAS No. 2559326-61-1

Description

Product Description

Lorutengitide (CAS 2559326-61-1) is a synthetic transcriptional regulatory peptide that exerts notable antiproliferative activity across various cellular models. Designed to interact with pathways governing transcriptional regulation, Lorutengitide has become a versatile research tool for exploring mechanisms underlying cell growth, differentiation, and oncogenesis.

Research Background

Transcriptional regulation plays a central role in maintaining cellular homeostasis. Aberrant transcriptional activity is one of the hallmarks of uncontrolled cell growth and tumor development. By modulating transcriptional signaling pathways, Lorutengitide provides a unique opportunity for researchers to study how targeted peptides can influence gene expression, cell cycle progression, and apoptosis.

Lorutengitide distinguishes itself from traditional small-molecule inhibitors by its peptide-based nature, which enhances selectivity and offers a tailored mechanism of action. This has important implications for preclinical investigations into targeted therapies.

Applications in Cancer Research

Lorutengitide’s antiproliferative efficacy positions it as a promising candidate for research into:

• Tumor growth inhibition through disruption of transcriptional signaling cascades.

• Synergistic use with chemotherapy or radiation therapy in preclinical models.

• Mechanistic studies on cancer cell apoptosis, autophagy, and survival pathways.

Molecular Biology Relevance

Beyond oncology, Lorutengitide supports research into fundamental molecular biology:

• Gene expression profiling to determine peptide impact on transcriptional activity.

• Signal transduction studies, particularly involving transcription factor modulation.

• Epigenetic regulation exploration, as transcriptional peptides may interact with chromatin remodeling.

Advantages as a Research Tool

• High specificity toward transcriptional pathways.

• Peptide design flexibility for analog development.

• Relevance across multiple cell systems, including human, animal, and microbial models.

Through these properties, Lorutengitide represents an innovative addition to peptide-based transcriptional modulators, creating opportunities for cutting-edge discoveries in both cancer and gene regulation research.

Product Specifications

Extended Notes:

• Purity: HPLC and mass spectrometry validated.

• Handling: Recommended sterile preparation for cell culture experiments.

• Application Spectrum: Oncology, molecular biology, and drug discovery.

Mechanism of Action

Lorutengitide acts primarily by modulating transcriptional regulation, targeting cellular signaling that governs gene expression and proliferation.

• Transcriptional Modulation
  It influences transcription factor activity and possibly interferes with promoter-binding mechanisms, altering downstream gene expression.

• Antiproliferative Pathway Activation
  By disrupting regulatory checkpoints, Lorutengitide triggers growth arrest in rapidly dividing cells, making it highly relevant in tumor models.

• Apoptotic Induction
  In some cellular models, Lorutengitide has been linked to the upregulation of pro-apoptotic pathways, facilitating programmed cell death.

• Potential Epigenetic Interactions
  Although still under research, transcriptional regulatory peptides may interact with chromatin structure, providing a secondary mechanism of action.

This combination of transcriptional control and growth inhibition makes Lorutengitide a versatile experimental compound in oncology and molecular biology.

Side Effects

Preclinical Safety

• Generally well tolerated in in vitro models.

• Minimal cytotoxicity reported outside targeted antiproliferative activity.

Potential Experimental Observations

• Growth Arrest: Expected in proliferating cell lines.

• Apoptosis: Dose-dependent induction in tumor models.

• Cytotoxic Effects: High concentrations may trigger nonspecific toxicity.

Precautions

• Results may vary by cell type.

• Should be handled with standard laboratory safety procedures.

• Not approved for therapeutic or diagnostic use.

Disclaimer

All information is provided for research and laboratory use only. Lorutengitide is not intended for human consumption, medical treatment, or diagnostic purposes.

Keywords

Lorutengitide peptide, CAS 2559326-61-1, transcriptional regulatory peptide, antiproliferative peptide, cancer biology research peptide, peptide transcription regulator, oncology peptide, laboratory research peptide.

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