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Memantine Hydrochloride Tablets 10?mg (Kougenite) – Dr. Reddy’s |
$2.00
Memantine Hydrochloride Tablets (brand: Kougenite ) contain 10?mg of Memantine HCl per tablet, packed as 28 tablets per box. Manufactured by Dr. Reddy’s Laboratories (India), these tablets are widely used in laboratory models of Alzheimer’s disease, neurodegeneration, and cognitive function research due to their action as NMDA receptor antagonists.?? For laboratory research only.?Please consult staff for other specifications and uses?
Description
Memantine is a non-competitive NMDA receptor antagonist, commonly studied for its neuroprotective effects in excitotoxicity-related models. It is used to simulate and counter glutamate-induced neurodegeneration, making it a valuable tool in research on Alzheimer’s disease, dementia, Parkinson’s-related cognitive decline, and traumatic brain injury models.
Memantine Hydrochloride Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Memantine Hydrochloride Tablets |
| Brand Name | Kougenite |
| Active Ingredient | Memantine Hydrochloride |
| CAS Number | 41100-52-1 |
| Molecular Formula | C12H21N·HCl |
| Molecular Weight | 215.76 g/mol |
| Formulation | Oral tablets |
| Strength | 10?mg per tablet |
| Pack Size | 28 tablets per box |
| Approval Number | HJ20220092 (NMPA, China) |
| Drug Code | 86978377000575 |
| Manufacturer | Dr. Reddy’s Laboratories Ltd. (India) |
| Storage Conditions | Store in a cool, dry place below 25?°C |
| Intended Use | For laboratory research only |
| Product Barcode | Available upon request |
Memantine Hydrochloride Mechanism of Action
Memantine selectively blocks N-Methyl-D-Aspartate (NMDA) receptors, which are involved in the pathophysiology of excitotoxicity caused by excessive glutamate. By inhibiting these receptors, Memantine helps prevent neuronal damage, thus allowing studies in:
Synaptic plasticity
Neuronal survival
Glutamate signaling pathway
Alzheimer’s and other CNS disorders
Memantine Hydrochloride Research Applications
Alzheimer’s Disease Models
Used to simulate therapeutic intervention in late-stage dementia and study memory retention and amyloid plaque activity.Neuroprotection Studies
Protects neurons against glutamate-induced excitotoxicity, allowing the study of apoptotic pathways.Cognition and Behavioral Models
Evaluates behavioral change in rodent models post cerebral ischemia or neurochemical insult.Parkinson’s-related Cognitive Decline
Investigates frontal-lobe executive function decline and associated neurochemical mechanisms.
Safety & Handling
Handling Guidelines: Use PPE including gloves, mask, and lab coat when handling.
Storage: Store sealed and protected from light and moisture.
Shelf Life: Stable under recommended storage for 24–36 months.
Toxicological Note: High concentrations may cause CNS effects—monitor dosage carefully in lab models.
Research Use Disclaimer
This product is intended exclusively for laboratory use. It is not authorized for use in humans, animals, or clinical diagnostics. Proper laboratory safety procedures must be followed at all times.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 26 × 23 × 26 cm |
Q1: What is Memantine used for in research?
A1: Memantine is primarily used in neurodegenerative disease research, especially Alzheimer's disease, for its role as an NMDA receptor antagonist.
Q2: What is the CAS number of Memantine HCl?
A2: The CAS number is 41100-52-1.
Q3: Is this Memantine formulation suitable for bulk research supply?
A3: Yes, we support wholesale and retail orders for academic institutions and pharmaceutical R&D.
Q4: Can it be used in humans or animals?
A4: No. This product is strictly for laboratory research and is not approved for therapeutic, diagnostic, or veterinary use.
Q5: Do you offer documentation like COA or SDS?
A5: Yes, Certificate of Analysis (COA) and Safety Data Sheet (SDS) are available upon request.
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