Description

Product Description

Myristoyl hexapeptide-16 (CAS 959610-54-9) is a synthetic lipid-modified bioactive peptide that combines a hexapeptide sequence with a myristoyl fatty acid moiety to increase its cellular penetration and biostability. It belongs to the class of signal and carrier peptides used in advanced cosmetic formulations for hair and eyelash enhancement research. Through its lipophilic chain, Myristoyl hexapeptide-16 efficiently interacts with the lipid barrier of the skin and hair follicles, enabling enhanced delivery of the peptide into deeper epidermal and follicular layers where it exerts its bioactivity.

In laboratory studies, Myristoyl hexapeptide-16 has been shown to promote the activation of hair follicle stem cells and the upregulation of key growth factors involved in folliculogenesis and keratin production. Its structure is designed to mimic natural peptide signals responsible for follicle proliferation and differentiation, thereby supporting research focused on enhancing eyelash density, length, and strength.

When applied in cosmetic research models, Myristoyl hexapeptide-16 has been observed to induce anagen phase extension (the active growth phase of hair), stimulate keratinocyte migration, and increase matrix cell activity around the hair bulb. This mechanistic profile makes it a valuable tool compound for studying non-hormonal pathways of hair and eyelash growth promotion.

The peptide’s lipid conjugation enhances its bioavailability and resistance to enzymatic degradation, allowing for sustained biological effects in in vitro and ex vivo models. Myristoyl hexapeptide-16 has also been studied for its ability to improve microcirculation around the hair follicle and enhance oxygen and nutrient delivery to the root area, further contributing to the appearance of thicker, stronger lashes.

Beyond its use in eyelash growth research, Myristoyl hexapeptide-16 is frequently explored for its anti-aging and dermal repair properties. Its biochemical activity supports extracellular matrix (ECM) remodeling by stimulating collagen and fibronectin production, helping restore skin elasticity and smoothness. When combined with other cosmetic peptides such as Myristoyl pentapeptide-17 and Acetyl hexapeptide-38, it may synergistically enhance cellular communication and improve overall dermal structure.

For research purposes, Myristoyl hexapeptide-16 is available as a high-purity ≥99% lyophilized powder (also known as freeze-dried powder or 冻干粉 in industry contexts), making it suitable for cosmetic raw material investigations in laboratories and R&D settings. Global researchers obtain this compound from factory peptide suppliers and China peptide manufacturers engaged in OEM & bulk peptide production, providing reliable sources for scientific testing and formulation work.

Product Specifications

Mechanism of Action

Myristoyl hexapeptide-16 operates as a lipidated signaling peptide that targets cellular receptors within the dermal papilla and epidermal stem cell zones of hair follicles. By enhancing the interaction between keratinocyte growth factors and extracellular matrix proteins, the peptide initiates a cascade of biochemical events that lead to hair growth activation.

At the molecular level, Myristoyl hexapeptide-16 upregulates the expression of vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF-1), and keratin-associated proteins (KRTs). These proteins are critical for hair follicle nourishment, angiogenesis, and structural stability. Research demonstrates that the peptide can enhance the activity of SMAD2/3 signaling, which is associated with cell proliferation and matrix protein synthesis.

The myristoyl moiety plays an essential role by facilitating the penetration of the peptide through the lipid barrier of the stratum corneum and anchoring it within the hydrophobic regions of the cell membrane. This lipophilic property increases local bioavailability and receptor binding potential.

Through these interactions, Myristoyl hexapeptide-16 stimulates mitochondrial activity within dermal fibroblasts and enhances energy metabolism, allowing cells to produce greater quantities of collagen and fibronectin. The result is improved tissue elasticity and skin structure support, which further stabilize the base of hair follicles and prevent premature shedding.

The peptide also modulates oxidative stress levels by scavenging free radicals and reducing reactive oxygen species (ROS), which are known to damage hair follicle cells and accelerate aging. This antioxidant property makes it an excellent candidate for studies focused on anti-aging and scalp rejuvenation.

Myristoyl hexapeptide-16 is often used in combination with other bioactive ingredients like Oligopeptide-41, Palmitoyl tripeptide-38, and Acetyl tetrapeptide-5 to investigate synergistic effects in cellular signaling and matrix formation. The combination approach is widely explored in cosmetic raw material research settings and by factory peptide suppliers engaged in OEM cosmetic development.

Side Effects

In research applications, Myristoyl hexapeptide-16 is considered non-toxic and biocompatible when used under controlled laboratory conditions. No adverse systemic effects have been reported in in vitro and ex vivo studies. Potential observations in model testing include mild temporary irritation at high concentrations or prolonged exposure periods.

Researchers should avoid direct application to mucous membranes or use outside approved cosmetic testing environments. Proper handling using laboratory protective equipment (gloves, eye protection) is recommended. As a synthetic research-grade compound, Myristoyl hexapeptide-16 is not intended for human use, injection, or clinical application.

Keywords

Myristoyl hexapeptide-16, CAS 959610-54-9, cosmetic peptide, hair growth peptide, eyelash enhancement research, anti-aging cosmetic peptide, factory peptide supplier, cosmetic raw material manufacturer, China peptide factory, high-purity peptide powder, OEM peptide production, bulk peptide supply.

Shipping Guarantee

All Myristoyl hexapeptide-16 shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We Myristoyl hexapeptide-16 ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We Myristoyl hexapeptide-16 provide flexible and secure global payment options to support international research transactions. Accepted methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All Myristoyl hexapeptide-16 products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.