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Nefopam Hydrochloride 20?mg ×?10 vials – Wholesale price comparison Research Use Only
$1.60
Nefopam Hydrochloride is a centrally acting, non-opioid analgesic with mild antipyretic and muscle-relaxant effects. Supplied as lyophilized powder (20?mg per 2?mL vial, 10 vials per box), this sterile injection is intended exclusively for laboratory and preclinical research. Not approved for therapeutic, diagnostic, clinical, or veterinary use.
Description
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Nefopam Hydrochloride Injection (Lyophilized) |
| Generic Name | Nefopam Hydrochloride |
| CAS Number | 13669?70?0 (Nefopam) 1mg.com+11en.wikipedia.org+11ryvispharma.com+11pubchem.ncbi.nlm.nih.gov |
| Chemical Formula | C??H??NO·HCl |
| Molecular Weight | ?289.8?g/mol |
| Dosage Form | Sterile lyophilized powder for reconstitution |
| Strength | 20?mg per 2?mL vial |
| Pack Size | 10 vials per box |
| Approval No. | China NMPA H37021048 |
| Product Code | 86904083000868 |
| Manufacturer | Shandong Faming Pharmaceutical Group Co., Ltd. |
| Barcode | 6935030530637 |
| Storage | Store at 2–25?°C; protect from light and moisture; reconstitute with sterile water |
| Intended Use | Laboratory research use only |
Mechanism of Action
Nefopam is a centrally acting analgesic that inhibits reuptake of serotonin, norepinephrine, and dopamine, and modulates glutamatergic pathways and sodium?calcium channels, providing non-opioid pain relief without respiratory depression .
Research Applications & Pharmacology
Acute and Post-Operative Pain Models: Effective for moderate to severe pain in preclinical models .
Chronic/Cancer Pain Studies: Used both in acute and chronic pain protocols .
Multimodal Analgesia: Frequently combined with opioids or NSAIDs to reduce opioid dosage and adverse effects .
Pharmacokinetics: Half-life ~3–8?hr; metabolized hepatically; excreted via urine (~79%) and feces (~13%) .
Safety Profile & Handling
Adverse Effects: May include nausea, sweating, dizziness, urinary retention, tachycardia, hallucinations, seizures (rare) .
Contraindications: History of epilepsy, myocardial infarction, narrow-angle glaucoma, MAO inhibitors, hypersensitivity .
Handling Prep: Reconstitute under aseptic conditions, inspect for clarity, do not mix with incompatible agents.
Storage/Preparation: Store vials sealed and protected; discard reconstituted solution per institutional protocols.
Additional information
| Weight | 1.1 kg |
|---|---|
| Dimensions | 18 × 16 × 18 cm |
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