Description
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Neostigmine Methylsulfate Injection (Fen Jie Song) |
| Generic Name | Neostigmine Methylsulfate |
| Formulation | Solution for Injection |
| Dosage Strength | 0.5?mg/mL |
| Pack Size | 5 ampoules × 1 mL |
| Dosage Form | Sterile injectable solution (lyophilized formulation) |
| Approval Number | H20233879 (NMPA, China) |
| Product Code | 86902181000964 |
| Barcode | 6950425900970 |
| Manufacturer | Chengdu Yuandong Biopharma Co., Ltd. |
| CAS Number | 51-60-5 |
| Storage | Store below 25?°C in a dry, light-protected environment |
| Intended Use | For laboratory research use only |
Mechanism of Action
Neostigmine methylsulfate is a reversible cholinesterase inhibitor that enhances acetylcholine availability at neuromuscular junctions. It binds to acetylcholinesterase, preventing the breakdown of acetylcholine, thereby improving synaptic transmission in cholinergic pathways.
Research Applications & Pharmacology
Studies in neuromuscular blockade reversal
Pharmacokinetics of acetylcholine dynamics
Autonomic nervous system modeling
Use in animal muscle response assays
Investigating interactions with muscarinic/nicotinic receptors
Research on myasthenia gravis analog models
Metabolism: Hepatic
Excretion: Primarily renal
Half-life: ~1–2 hours (species-dependent)
Safety Profile & Handling Instructions
Observed Effects in Preclinical Research:
Increased GI motility
Bradycardia, salivation, or muscle twitching
Hypotension in sensitive animal models
Lab Safety Guidelines:
Wear protective PPE (gloves, goggles, lab coat)
Do not inject or ingest
Avoid contact with eyes and mucosa
Dispose of vials per hazardous biomedical waste protocol
?? Research Use Disclaimer
This product is intended strictly for laboratory research purposes and is not approved for therapeutic, diagnostic, clinical, or veterinary use. Use only under authorized institutional biosafety guidelines.


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