Description
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Nicergoline Tablets (Dongyao / Shouning) |
| Generic Name | Nicergoline |
| CAS Number | 27848?84?6 |
| Molecular Formula | C??H??BrN?O? |
| Molecular Weight | 484.39?g/mol |
| Formulation | Oral tablet |
| Strength | 10?mg per tablet |
| Pack Size | 30 tablets per box |
| Approval Number | H20103155 (NMPA, China) |
| Manufacturer | Shandong Fangming Pharmaceutical Group Co., Ltd. |
| Barcode | 6935030530965 |
| Storage Conditions | Store at room temperature, protect from light and moisture |
| Intended Use | For laboratory research only |
Mechanism of Action
Nicergoline is a semi?synthetic ergot alkaloid that mainly acts as:
???adrenergic antagonist, causing vasodilation and improved cerebral blood flow
Enhances dopaminergic and serotonergic signalling, improving cognition
Inhibits platelet aggregation, supporting microcirculation
Displays neuroprotective effects, potentially modulating PI3K/Akt pathways
Research Applications & Pharmacology
Cerebral blood flow models: Used in stroke, subarachnoid hemorrhage, and cerebral ischemia assays
Cognitive function & neuroprotection: Employed in Alzheimer’s, dementia, memory decline, and oxidative stress models
Microcirculation & endothelial studies: Improves erythrocyte flexibility and reduces platelet aggregation
Pharmacodynamic assays: Ideal for ligand–receptor interactions, PDE inhibition, and ergot?based chemistry research
Safety Profile & Handling
Preclinical safety: Tolerated well; mild gastrointestinal symptoms and flushing reported in limited use
Lab precautions: Use gloves and masks; avoid inhalation or contact
Storage: Store sealed at room temperature, protect from light and humidity
Disposal: Dispose per institutional chemical waste protocols
Core Keywords
nicergoline tablets, CAS?27848-84-6, ergot derivative research chemical, cerebral vasodilator reagent, cognitive neuroscience reagent, neuroprotection assay compound, Dongyao Shouning nicergoline
Research?Use Disclaimer
This product is intended only for laboratory research purposes. It is not approved for clinical, therapeutic, diagnostic, or veterinary applications. Improper use may pose health risks. Always adhere to institutional safety protocols.


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