描述
Norepinephrine (noradrenaline) is an endogenous catecholamine and potent vasopressor, widely studied for its effects on blood pressure regulation, adrenergic receptor signaling, and stress-response pathways. The bitartrate salt form is commonly used for its solubility and pharmacodynamic consistency in preclinical models.
Each ampoule of Norepinephrine Bitartrate Injection contains 2mg of norepinephrine per 1ml. Supplied individually, this injectable is suitable for laboratory studies involving vascular tone modulation, shock modeling, and autonomic nervous system pharmacology.
This formulation is manufactured by Xi’an Lijun Pharmaceutical Co., Ltd., under China NMPA approval number H61021666, and product code 86902503002089.
Important: This product is for research use only. It is not for human or veterinary use.
Product Specifications
Parameter | Details |
---|---|
Product Name | Norepinephrine Bitartrate Injection |
Generic Name | Norepinephrine Bitartrate |
CAS Number | 108341-18-0 (bitartrate); 51-41-2 (norepinephrine base) |
Molecular Formula | C8H11NO3·C4H6O6 |
Molecular Weight | ~337.3 g/mol (bitartrate) |
Dosage Form | Injection (solution for injection) |
Strength | 2mg per 1ml |
Quantity | Single ampoule (1ml per unit) |
Approval Number | H61021666 (China NMPA) |
Product Code | 86902503002089 |
Manufacturer | Xi’an Lijun Pharmaceutical Co., Ltd. |
Intended Use | Laboratory research use only |
Storage Conditions | Store at 2–8°C; protect from light and moisture |
Mechanism & Research Applications
Norepinephrine functions primarily as a sympathomimetic agent, binding to ?-adrenergic and ?1-adrenergic receptors. It increases systemic vascular resistance and myocardial contractility, making it central to studies in cardiovascular physiology and pharmacology.
This injection is commonly used in:
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Preclinical models of septic or hypovolemic shock
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Studies of autonomic nervous system regulation
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Investigations of adrenergic receptor binding and signaling
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Vascular tone and reactivity studies
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Catecholamine interaction and neurotransmission experiments
Safety & Handling
Use Restriction: For laboratory research use only; not approved for therapeutic or diagnostic purposes.
Protective Equipment: Use gloves, lab coat, and safety goggles.
Storage: Store refrigerated (2–8°C) and protected from light.
Disposal: Dispose of in accordance with institutional chemical waste protocols.
Research Use Disclaimer
This product is intended strictly for laboratory research use. It is not approved for clinical, diagnostic, or veterinary use. Any misuse may lead to safety risks and regulatory violations. Always comply with local laws and biosafety standards.
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