Description

Norepinephrine bitartrate is a potent vasopressor agent commonly used in research to investigate blood pressure regulation, vascular response, and adrenergic receptor signaling. It functions as an alpha-adrenergic agonist, causing vasoconstriction and increased blood pressure.

This injectable solution contains 8mg of norepinephrine bitartrate per 4ml, supplied in 2 ampoules per box. The product is manufactured by Yuanda Pharma (China) Co., Ltd., and approved under NMPA registration number H20217065.

Note: For laboratory research use only. Not for human or animal administration.

Product Specifications

Mechanism & Research Applications

Norepinephrine acts on alpha-1 adrenergic receptors to induce vasoconstriction and raise peripheral resistance. It also activates beta-1 adrenergic receptors in the heart, increasing heart rate and contractility.

Used in experimental settings for:

• Septic shock and hypotension models

• Cardiovascular and hemodynamic studies

• Adrenergic pathway research

• Pharmacokinetic and receptor affinity analysis

Known Side Effects in Research Contexts

• Hypertension

• Reflex bradycardia

• Local tissue necrosis (with extravasation)

• Cardiac arrhythmias

• Anxiety or restlessness in vivo models

Safety & Handling Guidelines

• Intended Use: For laboratory research only

• Protective Equipment: Use gloves, lab coat, and eye protection

• Storage: Store at 2–8°C in a dark, sealed container

• Disposal: Follow hazardous chemical disposal protocols in your facility

Research Use Disclaimer

This product is intended strictly for research use only. It is not approved for human or veterinary use. Misuse may result in legal or safety risks. Handle in accordance with institutional safety standards and local regulations.