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NOTA-AE105 (CAS 1820563-84-5) – GMP Manufacturer
$2.00
NOTA-AE105 is a GMP-grade PET ligand (purity ? 98.91%) for the urokinase-type plasminogen activator receptor (uPAR), optimized for ??Cu or ??Ga radiolabeling. Available for wholesale and retail; for laboratory research use only.?For wholesale prices, other specifications and uses, please consult our staff?
Description
NOTA-AE105 is a synthetic peptide-based PET ligand for imaging urokinase-type plasminogen activator receptor (uPAR), a biomarker often elevated in tumors. It can be effectively radiolabeled with isotopes like ??Cu and ??Ga to produce high-contrast images and precise tumor delineation in preclinical models. Synthesized under GMP conditions with 98.91% purity, NOTA-AE105 is ideal for molecular imaging, cancer research, and radiopharmaceutical development. Strictly for research use only.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | NOTA-AE105 |
| Synonyms | uPAR PET ligand; NOTA-AE105 peptide |
| CAS No. | 1820563-84-5 |
| Purity | 98.91% (GMP-grade) |
| Molecular Formula | C??H???N??O?? |
| Molecular Weight | ~1511.68 Da |
| Appearance | White to off-white solid |
| Solubility | High solubility in DMSO (~83.3 mg/mL); water compatibility |
| Storage Conditions | Store lyophilized at –20 °C; aliquot solutions to avoid freeze-thaw |
| Manufacturing Standard | GMP-compliant |
| Applications | PET imaging, uPAR targeting, oncology research |
| Regulatory Status | For laboratory research use only |
Mechanism of Action & Research Applications
NOTA-AE105 binds selectively to uPAR, which is frequently overexpressed in tumors. When radiolabeled with ??Cu or ??Ga, it enables clear, high-contrast PET imaging of tumor sites. Its high affinity and GMP production make it a valuable tool for molecular imaging studies in oncology and translational research.
Disclaimer
This product is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Handle according to institutional safety protocols.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 53 × 42 × 53 cm |
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