Description

Product Description

Oligopeptide-20 is a synthetic bioactive peptide sequence that plays a vital role in promoting skin repair, regeneration, and rejuvenation processes. It functions as a powerful cellular communication modulator, encouraging fibroblast activity, extracellular matrix reconstruction, and collagen synthesis. This peptide has been widely studied in cosmetic peptide research for its ability to restore tissue integrity after environmental damage, UV exposure, or inflammatory conditions.

In the context of advanced skin biology, Oligopeptide-20 demonstrates a multifaceted mechanism that supports both epidermal and dermal renewal. It aids in enhancing cell turnover, strengthening the skin barrier, and improving elasticity. These attributes make it a valuable peptide for exploring formulations focused on wound healing, tissue regeneration, and anti-aging research.

Oligopeptide-20 helps to reactivate the natural repair signaling within skin cells by mimicking endogenous growth factors. Through this biomimetic activity, it can accelerate fibroblast proliferation, increase type I and III collagen synthesis, and promote elastin production. This process leads to improved dermal density, reduced fine lines, and better hydration retention, which are key factors in maintaining youthful skin structure.

Researchers investigating the molecular pathways of Oligopeptide-20 have found that it modulates the expression of matrix metalloproteinases (MMPs), reducing collagen degradation and supporting extracellular matrix preservation. Its antioxidant potential also contributes to neutralizing free radicals, thereby protecting cells from oxidative stress and photoaging effects.

In vitro studies suggest that Oligopeptide-20 enhances keratinocyte differentiation and migration, contributing to faster epidermal regeneration after damage. This makes it a promising subject in scientific research on skin barrier restoration and cosmetic wound-healing mechanisms.

Product Specifications

Mechanism of Action

Oligopeptide-20 exerts its biological effect through cellular signaling pathways involved in wound healing and extracellular matrix remodeling. Acting as a biomimetic peptide, it mimics natural growth factor sequences that communicate with fibroblasts, stimulating them to produce structural proteins such as collagen and elastin.

At the molecular level, Oligopeptide-20 interacts with fibroblast surface receptors, activating the TGF-β (Transforming Growth Factor Beta) pathway. This activation triggers SMAD signaling, which enhances gene expression responsible for the production of collagen types I and III. Consequently, the peptide aids in restoring dermal thickness and firmness.

Additionally, Oligopeptide-20 has been shown to upregulate fibronectin synthesis, which plays a crucial role in tissue adhesion and repair. This contributes to the stabilization of new extracellular matrix structures and improves mechanical resilience in the dermal layer.

The peptide also plays a preventive role against premature aging by suppressing MMP-1 and MMP-9 enzymes that break down collagen. This anti-degradative action maintains dermal integrity and minimizes wrinkle formation. In oxidative stress models, Oligopeptide-20 demonstrates antioxidant activity by scavenging free radicals and protecting mitochondrial function.

Moreover, Oligopeptide-20 supports keratinocyte proliferation and differentiation, ensuring balanced epidermal regeneration. Its dual impact on dermal and epidermal levels provides a comprehensive model for studying barrier restoration, moisture retention, and anti-aging processes in cosmetic research.

Side Effects

Under controlled laboratory conditions, Oligopeptide-20 is generally considered safe for in vitro and ex vivo research applications. No significant cytotoxic effects have been observed in cell culture models within recommended concentration ranges. However, excessive dosing may lead to cell stress or receptor desensitization.

As with all peptides, researchers should ensure appropriate sterile handling and avoid repeated freeze–thaw cycles to maintain peptide integrity. In vivo testing should be conducted strictly under institutional ethics guidelines, and no human application should be inferred from laboratory data.

All safety and toxicity assessments indicate that Oligopeptide-20 maintains high biocompatibility, making it an ideal candidate for academic and industrial cosmetic peptide research.

Keywords

Oligopeptide-20, CAS 948884-07-9, skin repair peptide, collagen synthesis peptide, cosmetic peptide supplier, China peptide factory, anti-aging peptide, peptide raw material manufacturer, high-purity cosmetic peptide, OEM bulk peptide production, skin regeneration peptide, wound healing peptide, peptide research supplier.

Shipping Guarantee

All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We Oligopeptide-20 ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We Oligopeptide-20 provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All Oligopeptide-20 products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.