Description

Product Description

Oligopeptide-74 is a synthetic bioactive peptide with demonstrated hair growth-promoting properties. As a key component in cosmetic research, it has shown the ability to stimulate proliferation in dermal papilla cells, enhance keratinocyte activity, and modulate the extracellular matrix to support follicle integrity. Its activity is particularly relevant for studies targeting hair loss, hair thinning, and scalp health.

The peptide acts at multiple levels:

1. Cellular proliferation: Oligopeptide-74 increases dermal papilla cell viability, which is essential for the maintenance and growth of hair follicles.

2. Extracellular matrix support: By stimulating collagen, elastin, and glycosaminoglycan deposition, it promotes the structural foundation necessary for hair follicle anchoring.

3. Signal modulation: Oligopeptide-74 interacts with intracellular signaling pathways related to hair follicle cycling and growth, including Wnt/β-catenin and other growth factor networks.

In addition to hair follicle activity, Oligopeptide-74 exhibits antioxidant potential, reducing oxidative stress in the scalp environment. Oxidative stress is known to accelerate follicular aging and hair loss; therefore, antioxidant peptides like Oligopeptide-74 play a role in mitigating this process.

As a cosmetic research ingredient, Oligopeptide-74 is water-soluble, highly stable, and compatible with various formulations, including serums, lotions, and topical peptide complexes. Its high purity (≥99%) ensures reproducibility in research and experimental applications, minimizing variability that could arise from impurities.

Overall, Oligopeptide-74 serves as a model peptide for studying hair regeneration mechanisms, dermal cell signaling, and extracellular matrix remodeling, making it highly valuable for laboratories focused on cosmetic peptide innovation and hair care solutions.

Product Specifications

Mechanism of Action

Oligopeptide-74 promotes hair growth and scalp health through multiple synergistic mechanisms:

1. Stimulation of Dermal Papilla Cells (DPCs):
   Dermal papilla cells are critical regulators of hair follicle development and growth. Oligopeptide-74 increases DPC proliferation and viability, prolonging the anagen (growth) phase of the hair cycle. Enhanced DPC activity leads to more robust follicular function and hair shaft production.

2. Extracellular Matrix (ECM) Enhancement:
   The extracellular matrix surrounding hair follicles provides structural support and modulates cellular signaling. Oligopeptide-74 upregulates the synthesis of collagen types I and III, elastin, laminin, and glycosaminoglycans. These components improve follicular anchoring and resilience, preventing hair miniaturization.

3. Signal Pathway Modulation:
   Oligopeptide-74 interacts with key signaling pathways, including Wnt/β-catenin, fibroblast growth factor (FGF), and vascular endothelial growth factor (VEGF) pathways. By promoting these pathways, the peptide facilitates hair follicle regeneration and microvascular support to the scalp.

4. Antioxidant and Protective Effects:
   Oxidative stress contributes to follicle senescence and hair loss. Oligopeptide-74 exhibits ROS-scavenging activity, reducing damage to follicular keratinocytes and dermal papilla cells, thus maintaining healthy follicle cycles.

5. Collagen and Elastin Modulation:
   By increasing collagen and elastin deposition in the scalp dermis, Oligopeptide-74 strengthens follicular support structures, indirectly enhancing hair density and thickness.

6. Synergistic Interaction with Other Bioactives:
   Oligopeptide-74 has been reported to act synergistically with other peptides and growth factors, amplifying anti-aging and hair growth effects in cosmetic research applications.

These combined mechanisms underline Oligopeptide-74 as a potent research peptide for hair rejuvenation, anti-aging scalp studies, and the exploration of novel cosmetic formulations.

Side Effects

Oligopeptide-74 has been evaluated primarily in in vitro and preclinical models. Reported observations include:

• Low cytotoxicity: Studies indicate minimal cytotoxic effects on dermal papilla and keratinocyte cultures at standard experimental concentrations.

• Skin compatibility: No adverse skin reactions were reported in topical formulations under laboratory research conditions.

• Safety profile: While high purity ensures reproducibility, all laboratory safety protocols should be followed when handling lyophilized peptide powders.

• Handling precautions: Use personal protective equipment (PPE) and avoid inhalation or direct contact with skin and eyes.

As with all experimental peptides, Oligopeptide-74 is for laboratory research use only and not intended for human or veterinary administration. Researchers should strictly follow institutional biosafety and chemical safety guidelines.

Keywords

Oligopeptide-74, hair growth peptide, cosmetic peptide, dermal papilla activator, scalp rejuvenation, anti-aging peptide, high purity peptide

Shipping Guarantee

All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.