Paclitaxel Polymeric Micelle Injection 30?mg -Shanghai Yizhong
$2.00
Paclitaxel polymeric micelle injection is an innovative nano?formulation developed by Shanghai Yizhong Pharmaceutical Co. using narrow?distribution polymer excipients to form stable micelles—no pre?medication required. Each vial contains 30?mg of paclitaxel in lyophilized form. Approved by China NMPA H20210047 (Product Code 86982039000018).
?? For laboratory research use only. ?Please consult the staff for other purposes?
描述
Paclitaxel Polymeric Micelle Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Paclitaxel Polymeric Micelle Injection |
| Generic Name | Paclitaxel |
| Dosage Form | Lyophilized polymeric micelle injection |
| Strength | 30?mg per vial |
| Pack Size | 1 vial per box |
| Approval Number | H20210047 (China NMPA) |
| Product Code | 86982039000018 |
| Manufacturer | Shanghai Yizhong Pharmaceutical Co., Ltd. |
| Barcode | 6974929830014 |
| CAS Number | 33069?62?4 |
| Storage | Store at 2–8?°C, protect from light and moisture |
| Intended Use | Laboratory research only |
Paclitaxel Polymeric Micelle Mechanism of Action
Paclitaxel binds to microtubules and stabilizes them, preventing their depolymerization and blocking cell division. The polymeric micelle formulation improves solubility and eliminates Cremophor, reducing hypersensitivity risk .
Research Applications & Pharmacology
-
Nano-oncology research: Enhanced delivery models in vitro and in vivo
-
Pharmacokinetics: Linear PK in phase I Chinese patients; dose-limiting toxicity is neutropenia; MTD at 350?mg/m² without hypersensitivity pubmed.ncbi.nlm.nih.gov
-
Clinical indications: Approved for first-line EGFR-negative, ALK-negative NSCLC in combination with platinum—no premedication needed nhsa.gov.cn+2sse.com.cn+2cdek.pharmacy.purdue.edu+2
-
Emerging uses: Studies in metastatic breast and pancreatic cancer, HER2- disease zh.wikipedia.org
Safety Profile & Side Effects
Adverse events observed in NSCLC study:
-
Hematologic: Grade 4 neutropenia (28.7%), thrombocytopenia (1.7%)
-
Hypersensitivity: mild (~1.3%), no severe reactions reported
-
Neurologic: peripheral neuropathy (~40.7%)
-
GI: nausea, diarrhea, mucositis (?5%)
-
Others: alopecia, skin rash, myalgia, arthralgia, infusion?site reactions, mild hepatotoxicity and nephrotoxicity
?? Research-Use Disclaimer
This product is exclusively for laboratory research use and not approved for diagnostic, therapeutic, clinical, or veterinary use. Improper application may present risks and invalidate experimental data.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
相关产品
-
Limertinib Tablets 80?mg ×?20 – by Osscon Pharma | Research Use Only (3rd?Gen EGFR?TKI)
Limertinib (OuyiXin®) is a third-generation EGFR tyrosine kinase inhibitor (EGFR?TKI) at 80?mg per tablet, 20 tablets per box, from Jiangsu Osscon Pharmaceutical. Approved by China’s NMPA under H20250004, it targets EGFR T790M?mutated non?small cell lung cancer, including patients with brain metastases.
?? For research use only – Not for human consumption or therapeutic use. $1.00 -
Propranolol Hydrochloride Oral Solution 40?mg/5?mL Research & Analytical Use
Propranolol Hydrochloride Oral Solution (HeMeiJia) offers a sweet strawberry-mint 40?mg/5?mL formulation in a 40?mL bottle. Approved by NMPA under H20213549, this solution provides accurate dosing—ideal for infantile hemangioma, pediatric cardiovascular, or pharmacokinetic studies.
$1.00
?? For laboratory research or analytical purposes only – Not for therapeutic use. -
Rilertinib Mesylate Tablets (Sanrisso®) – 100?mg × 20 Tablets per Bottle
Rilertinib mesylate (Sanrisso®), developed by Nanjing Sanhome Pharmaceutical Co., Ltd., is a third-generation EGFR-TKI approved by China's NMPA (Approval No. H20240020; Drug Code: 86901583000930). Each bottle contains 20 tablets of 100?mg each. Strictly for laboratory research use only—not for clinical or human use. $1.00 -
Palbociclib Capsules (Xipeilai) – 125?mg, 21 Capsules Price comparison
Palbociclib Capsules (Research Grade) in 125?mg strength, 21-count bottle. Supplied by Shanghai Chuannuo Pharmaceutical Co., Ltd. For investigational or research applications only—not for human consumption or therapeutic use.
$2.00
评价
目前还没有评价