Description

Product Description

Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine is a bioactive peptide widely recognized in cosmetic research for its robust anti-aging properties. Structurally, it is a palmitoylated dipeptide conjugated with diaminobutyroyl hydroxythreonine, designed to enhance skin penetration and stability. This peptide mimics the biological activity of naturally occurring signaling molecules in the skin, stimulating fibroblast function and extracellular matrix synthesis.

Skin Regeneration and Collagen Stimulation

Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine promotes dermal fibroblast proliferation and increases collagen type I and III production. This action contributes to reducing the appearance of fine lines and wrinkles, improving skin firmness, and restoring elasticity. By interacting with fibroblast surface receptors, it upregulates signaling pathways critical for extracellular matrix remodeling and repair.

Anti-Aging Mechanisms

The peptide inhibits enzymes responsible for collagen degradation, such as matrix metalloproteinases (MMPs), and stimulates growth factors that reinforce skin structural integrity. Regular application in topical formulations enhances skin smoothness, diminishes sagging, and promotes a youthful appearance.

Moisture Retention and Skin Barrier Support

Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine improves skin hydration by enhancing glycosaminoglycan synthesis and reinforcing the stratum corneum barrier. It has demonstrated an ability to reduce transepidermal water loss (TEWL) in cosmetic studies, contributing to long-term skin health.

Research Applications

This peptide is widely used in studies exploring anti-aging, skin regeneration, collagen stimulation, and barrier function enhancement. Its high stability and skin permeability make it ideal for evaluating the efficacy of cosmetic formulations targeting mature or damaged skin.

Product Specifications

Mechanism of Action

Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine acts as a biomimetic signaling peptide that stimulates skin fibroblasts, promoting the synthesis of collagen types I and III and other extracellular matrix proteins such as elastin and fibronectin. By mimicking the body’s endogenous repair signals, it activates growth factor-mediated pathways and reinforces the skin’s structural network.

The peptide inhibits MMP enzymes, preventing collagen breakdown, and enhances glycosaminoglycan production, improving hydration and elasticity. Additionally, it upregulates anti-inflammatory cytokines, reducing oxidative stress-related damage in dermal tissues.

Mechanistic studies suggest that palmitoylation enhances cell membrane permeability, facilitating intracellular signaling interactions. This dual functionality—stimulating repair while protecting against degradation—makes it a powerful anti-aging ingredient in cosmetic research.

Side Effects

Palmitoyl dipeptide-5 diaminobutyroxythreonine is well tolerated in vitro and in cosmetic applications. Reported side effects are minimal due to its biomimetic nature and high specificity for fibroblast signaling pathways. Some topical studies note mild transient erythema in sensitive skin models, but no cytotoxic effects or irritation have been observed in standard dermatological tests.

Keywords

Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine, anti-aging peptide, skin regeneration, collagen stimulator, cosmetic peptide, high purity, hair and skin research, lyophilized powder, China peptide manufacturer, low-price peptide supplier

Shipping Guarantee

All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.