Description

Product Description

Palmitoyl dipeptide-5 diaminohydroxybutyrate is a synthetic lipopeptide composed of a dipeptide linked to a palmitic acid chain. This structure enhances its lipophilicity and bioavailability, allowing better penetration into the epidermal and dermal layers of the skin. The compound has gained significant attention in cosmetic science as an advanced bioactive ingredient for anti-aging and dermal repair research.

As part of the next generation of biomimetic peptides, Palmitoyl dipeptide-5 diaminohydroxybutyrate mimics the activity of natural matrikines—small protein fragments that signal skin cells to repair and rejuvenate the extracellular matrix (ECM). The ECM is essential for maintaining the skin’s firmness, elasticity, and moisture retention. With age, degradation of collagen and elastin leads to sagging, wrinkles, and reduced skin tone. By stimulating ECM synthesis, this peptide helps restore skin’s youthful structure.

Studies in cosmetic science suggest that Palmitoyl dipeptide-5 diaminohydroxybutyrate significantly increases the synthesis of essential proteins such as collagen I, collagen IV, fibronectin, and laminin. These are crucial for the dermal-epidermal junction, which provides structural support and facilitates communication between skin layers. Strengthening this junction results in visible improvements in skin texture, tone, and elasticity.

Moreover, this peptide has shown anti-glycation activity. Glycation, the process where sugar molecules bind to proteins, contributes to skin aging by making collagen fibers stiff and brittle. By counteracting glycation, Palmitoyl dipeptide-5 diaminohydroxybutyrate helps maintain the skin’s flexibility and natural resilience.

Its molecular design also promotes cell-to-cell adhesion and enhances the cohesion of the stratum corneum, supporting barrier integrity. This makes it an excellent research target for formulating products aimed at mature or sensitive skin.

In summary, Palmitoyl dipeptide-5 diaminohydroxybutyrate is a scientifically supported cosmetic peptide known for its dual function: stimulating collagen and elastin synthesis while strengthening the skin barrier. Its ability to enhance firmness and smoothness makes it ideal for anti-aging, firming, and restorative skincare research.

Product Specifications

Mechanism of Action

The mechanism of Palmitoyl dipeptide-5 diaminohydroxybutyrate revolves around its signaling function as a biomimetic peptide that interacts with fibroblasts in the dermis. When topically applied or introduced in vitro, it activates genes related to extracellular matrix protein synthesis, notably collagen and elastin.

1. Collagen and Elastin Stimulation:
   The peptide promotes the synthesis of structural proteins, particularly collagen I and elastin, which maintain dermal density and elasticity. Enhanced collagen production strengthens the skin matrix, reducing sagging and wrinkles.

2. Barrier Function Reinforcement:
   By increasing the expression of laminin and integrins, it strengthens the dermal-epidermal junction, improving overall skin cohesion and reducing trans-epidermal water loss.

3. Anti-Glycation and Oxidative Protection:
   Palmitoyl dipeptide-5 diaminohydroxybutyrate inhibits glycation-induced damage by reducing the formation of advanced glycation end-products (AGEs). It also enhances the antioxidant capacity of skin cells, helping neutralize free radicals that contribute to aging.

4. Enhanced Bioavailability via Palmitoylation:
   The addition of a palmitic acid moiety improves lipophilicity, ensuring better skin penetration and longer-lasting biological activity.

5. Regeneration of Dermal Structure:
   Regular use in research models has shown increased dermal thickness and smoother surface topography, aligning with its role in skin rejuvenation and repair.

This peptide’s multifaceted mechanism aligns with its growing use in cosmetic formulations focused on skin firmness, wrinkle reduction, and recovery of youthful skin structure.

Side Effects

In research settings, Palmitoyl dipeptide-5 diaminohydroxybutyrate has exhibited a strong safety profile. Cytotoxicity tests on fibroblasts and keratinocytes reveal no significant adverse reactions at standard cosmetic concentrations (≤0.005%).

Potential considerations include:

• Skin Sensitivity: Mild transient irritation in sensitive models may occur at high concentrations.

• Allergic Reactions: As with all peptides, patch testing is advised to rule out peptide-specific hypersensitivity.

• Storage Stability: Improper storage (exposure to heat or humidity) can lead to peptide degradation, reducing efficacy.

Overall, the peptide is well tolerated and widely regarded as suitable for research into skin anti-aging and dermal renewal.

Keywords

Palmitoyl dipeptide-5 diaminohydroxybutyrate, anti-aging peptide, cosmetic peptide, collagen stimulator, wrinkle reduction, elastin booster, skin repair, factory peptide supplier, peptide wholesale China, cosmetic raw material manufacturer, high-purity peptide, OEM & bulk peptide production.

Shipping Guarantee

All Palmitoyl dipeptide-5 diaminohydroxybutyrate shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We Palmitoyl dipeptide-5 diaminohydroxybutyrate ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We Palmitoyl dipeptide-5 diaminohydroxybutyrate provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All Palmitoyl dipeptide-5 diaminohydroxybutyrate products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.