描述
Pamidronate Disodium Injection Description
Product name: Pamidronate disodium for injection
Packing specification: 15mg*10 bottles ? Product dosage form: injection ? Packing unit: box
Approval number: National medicine standard H20093151 ? Drug standard code: 86902066001833
Manufacturer: Chengdu Tiantaishan Pharmaceutical Co., Ltd.
Pamidronate Disodium (pamidronic acid) is a second-generation nitrogen-containing bisphosphonate clinically used to prevent bone loss, treat osteoporosis, Paget’s disease, hypercalcemia of malignancy, and multiple myeloma-related bone disease?patents.google.com+12en.wikipedia.org+12prospectresearchreports.com+12.
This injection contains 15?mg of active compound per vial, intended for intravenous infusion in research settings exploring:
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Bone resorption and metabolism
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Neoplastic bone lesions
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Calcium homeostasis
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Bisphosphonate-related side effects such as osteonecrosis of the jaw and hypocalcemia?
Clinical pharmacokinetics show protein-binding ~54%, renal elimination, and a long half-life (~28?±?7?h), making it suitable for steady-state dosing and mechanistic studies?en.wikipedia.org.
? Product Specifications
Feature | Details |
---|---|
Product Name | Pamidronate Disodium Injection |
Strength | 15?mg pamidronate per vial |
Quantity | 10 vials per box |
Formulation | Sterile aqueous solution for IV infusion |
Manufacturer | Chengdu Tiantai Shan Pharmaceutical Co., Ltd. |
Approval Number (NMPA) | H20093151 |
Product Code | 86902066001833 |
Storage | Store at 2–8?°C; protect from freeze and light |
Shelf Life | 24 months (as per packaging) |
Appearance | Clear, colorless solution |
Administration Route | Intravenous infusion after dilution |
Pharmacokinetics | Protein bound 54%, renal excretion, elimination half-life ~28?h |
?? Mechanism of Action & Key Benefits
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Bone preservation: Inhibits osteoclast-mediated bone resorption, reducing skeletal-related events?.
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Clinical relevance: Doses of 30–90?mg monthly empower research in osteolytic conditions and hypercalcemia studies?.
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Rich pharmacokinetics: High protein binding and renal clearance favor predictable blood levels in models?.
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Side effect profiling: Common adverse reactions include fever, bone pain, hypocalcemia, and gastrointestinal upset—valuable for mechanistic toxicity research?.
? Why Choose This Product?
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Approved and traceable by NMPA
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Pharma-grade single-dose vials for convenient use
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Supports robust research in bone disease, oncology, and metabolism
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Ideal for chronic dosing or pharmacokinetic investigations
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Zoledronic Acid Injection (Bisphosphonate)
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Alendronate Sodium for Injection
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Denosumab for Injection (RANKL Inhibitor)
? Summary
Pamidronate Disodium 15?mg Injection by Chengdu Tiantai Shan Pharma is a reliable research-grade tool for bone metabolism, oncology, and calcium homeostasis studies. With high-quality manufacture, clear pharmacokinetic profile, and injectable format, it’s suitable for a variety of lab models.
?? For laboratory research or analytical use only — not for human consumption or therapy.
mamr –
Not bad, thank you