No products in the cart.
Parecoxib Sodium 40?mg × 10 Vials Wholesale price comparison
$1.00
Parecoxib sodium is a water-soluble injectable prodrug of valdecoxib—a selective COX?2 inhibitor—widely used in perioperative pain and inflammation research. Each vial contains 40?mg parecoxib sodium. Manufactured by Hunan Sailong Pharma (Changsha) Co., Ltd., approved under NMPA H20193217, product code 86979286000151, barcode 6973398250095.
?? For laboratory research use only.?Please consult the staff for other purposes?
Description
Parecoxib-Sodium Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Parecoxib Sodium Injection (Saishulin®) |
| Generic Name | Parecoxib Sodium |
| CAS Number | 15895902 (parecoxib sodium) sciencedirect.com+7en.wikipedia.org+7synapse.patsnap.com+7pubchem.ncbi.nlm.nih.gov |
| Molecular Formula | C??H??N?NaO?S |
| Molecular Weight | ~370.4?g/mol (salt) |
| Dosage Form | Lyophilized powder for IV/IM injection |
| Strength | 40?mg per vial |
| Pack Size | 10 vials per box |
| Approval Number | H20193217 (China NMPA) |
| Product Code | 86979286000151 |
| Manufacturer | Hunan Sailong Pharma (Changsha) Co., Ltd. |
| Barcode | 6973398250095 |
| Storage | Store at 2–8?°C; protect from light |
| Intended Use | Laboratory research use only |
Mechanism of Action
Parecoxib is an injectable prodrug rapidly converted into valdecoxib in the liver, which selectively inhibits COX?2, reducing prostaglandin-mediated pain and inflammation, while sparing COX?1 activity.
Research Applications & Pharmacology
Perioperative pain models: IV or IM administration at 20–40?mg produces rapid analgesia within 7–14 minutes and lasts up to 24 hours; comparable to ketorolac or morphine.
Anti-inflammatory studies: Suppresses prostaglandin synthesis, COX?2 pathways, and inflammatory mediators (e.g., IL?1?, IL?6); reduces oxidative stress and postoperative delirium in elderly models .
Pharmacokinetics: Parecoxib half-life ~22 min; conversion to valdecoxib with ~8?hr half?life; high protein binding (~98%); excreted primarily in urine.
Safety Profile & Handling
Reported effects:
Rapid analgesic onset with minimal platelet impact .
Typical COX?2 NSAID risks: GI ulcers, renal impairment, cardiovascular effects; dose-dependent hypotension noted .
Handling guidelines:
Reconstitute vial with 0.9% NaCl or 5% glucose; administer IV bolus or IM slowly and deeply; flush line before/after use .
Use PPE, monitor subjects for hemodynamic and renal/hepatic changes.
Dispose of waste as pharmaceutical hazardous material.
?? Research?Use Disclaimer
This product is intended solely for laboratory research. It is not approved for clinical, therapeutic, diagnostic, or veterinary use. Misuse may pose health risks and COVID compliance issues, and may compromise research integrity.
Additional information
| Weight | 1.1 kg |
|---|---|
| Dimensions | 18 × 16 × 18 cm |
Related products
Ropivacaine Mesylate 4?mg ×?5 Ampoules Wholesale price comparison
Ropivacaine is a long-acting amide local anesthetic featuring a pure S?enantiomer profile that provides sensory-specific blocking while minimizing motor blockade. Supplied as five 4?mg ampoules per box, produced by Xi’an Hanfeng Pharmaceutical Co., Ltd. Approved under China NMPA H20060477, product code 86902499000120, barcode 6947954800208.
?? For laboratory research use only?Please consult staff for other specifications and uses? $2.00Drotaverine Hydrochloride 40?mg ×?5 Vials Wholesale price comparison
Drotaverine is a spasmolytic PDE4 inhibitor used in preclinical research to relieve smooth muscle spasms—gastrointestinal, biliary, urinary, and uterine. Each vial contains 40?mg in 2?mL solution. Manufactured by Chongqing Shenghuaxi Pharmaceutical Co., Ltd., approved under NMPA H20183353, product code 86909568000197, barcode 6933982500616.
?? For laboratory research use only.?Please consult the staff for other purposes? $2.00Levobupivacaine Hydrochloride 37.5?mg ×?5 Vials Wholesale price comparison
Levobupivacaine is the S?enantiomer of bupivacaine, a long?acting amide?type local anesthetic offering reduced cardiotoxicity and prolonged nerve blockade. Each 5?mL vial contains 37.5?mg. Produced by Yichang Renfu Pharmaceutical Co., Ltd., approved under NMPA H20193347, product code 86902000002308, barcode 6930829980983.
?? For laboratory research use only.?Please consult the staff for other purposes? $1.00Bupivacaine Hydrochloride 37.5?mg ×?5 Vials Wholesale price comparison
Bupivacaine hydrochloride is a long-acting amide-type local anesthetic widely used in preclinical studies for nerve block, infiltration, epidural, and spinal anesthesia. Each box contains five 5?mL vials (37.5?mg per vial). Manufactured by Hunan Zhengqing Pharmaceutical Group Co., Ltd., approved under NMPA H43021018, product code 86904152004254.
?? For laboratory research use only.?Please consult the staff for other purposes? $2.00
Reviews
There are no reviews yet.