Description
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) widely used in pharmacological research related to mood regulation, depression models, and behavioral neuroscience. The sustained-release enteric coating ensures controlled release, making it suitable for long-term in vivo research models.
This formulation provides consistent plasma concentration modeling, useful in evaluating antidepressant efficacy, tolerance, and receptor binding over time in lab settings.
Product Specifications
| Attribute | Detail |
|---|---|
| Product Name | Paroxetine Hydrochloride SR Tablets (Xinliping) |
| Generic Name | Paroxetine Hydrochloride Enteric-Coated Sustained-Release Tablets |
| CAS Number | 61869-08-7 |
| Molecular Formula | C??H??FNO?·HCl |
| Molecular Weight | 365.83?g/mol |
| Strength | 12.5?mg per tablet |
| Formulation | Enteric-coated sustained-release tablet |
| Packaging | 30 tablets per box |
| Dosage Form | Tablet |
| Approval Number | H20203423 (China NMPA) |
| Pharmaceutical Code | 86900553000895 |
| Manufacturer | Shenzhen Salubris Pharmaceuticals Co., Ltd. |
| Barcode | 6923830503432 |
| Storage Conditions | Store in a cool, dry place below 25?°C |
| Intended Use | For laboratory research only |
Mechanism of Action
Paroxetine selectively inhibits the reuptake of serotonin (5-HT) in presynaptic neurons, increasing serotonin levels in the synaptic cleft. This action makes it valuable in studying neurochemical mechanisms of depression, obsessive-compulsive behavior, and generalized anxiety models. The sustained-release form allows for consistent plasma levels in long-term animal models.
Research Applications
Behavioral studies on depression and anxiety
Pharmacokinetics of SSRIs
Receptor binding studies in neuropharmacology
In vivo models of serotonin dysfunction
Comparison with other antidepressants (e.g., fluoxetine, sertraline)
Safety & Handling Guidelines
Observed Effects: Lethargy, gastrointestinal changes, reduced appetite in animal models
Handling: Use lab PPE. Avoid inhalation or skin exposure
Storage: Store in original packaging at room temperature, away from light and moisture
Research Use Disclaimer
This product is strictly for scientific and laboratory research. Not for use in humans or animals for therapeutic purposes. Use in accordance with institutional biosafety and chemical handling protocols.


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