Progesterone Injection (II) 25?mg / 1.112?mL × 7 vials Subtotal: $1.00
Pemetrexed Disodium Injection (Qilu/Saizhen®) – 0.2?g × 4 Vials Wholesale price comparison
$1.00
Pemetrexed is a multi-targeted antifolate chemotherapeutic agent supplied as 200?mg freeze-dried powder per vial (4 vials/box). Manufactured by Qilu Pharmaceutical Co., Ltd., approved in China (NMPA No.?H20060672; Product Code:?86904021001339; Barcode:?6915798000580). Strictly for laboratory research use only?Please consult the staff for other purposes?
描述
Pemetrexed Disodium Injection Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Pemetrexed Disodium Injection (Qilu/Saizhen®) |
| Strength | 0.2?g per vial (freeze-dried powder) |
| Formulation | Injectable lyophilized powder, dissolve in saline |
| Package | 4 vials per box |
| Approval No. | China NMPA H20060672 |
| Product Code | 86904021001339 |
| Barcode | 6915798000580 |
| Manufacturer | Qilu Pharmaceutical Co., Ltd. |
| Intended Use | Laboratory research only — Not for human or veterinary use |
Pemetrexed Disodium Injection Mechanism of Action
Pemetrexed is a multi-target antifolate that inhibits key folate-dependent enzymes—thymidylate synthase (TS), dihydrofolate reductase (DHFR), and GARFT—disrupting DNA and RNA synthesis in rapidly dividing cells en.wikipedia.org It’s transported into cells via folate carriers and retained by polyglutamation
Research & Pharmacological Insights
-
Clinically used (500?mg/m² IV infusion every 21 days) to treat nonsquamous NSCLC and malignant pleural mesothelioma, often combined with cisplatin or pembrolizumab
-
Side effects include myelosuppression, nausea, fatigue, and risk of interstitial pneumonitis .
-
In preclinical models, pemetrexed shows potent antitumor activity through folate-pathway inhibition and is a standard tool in metabolic pathway research
Research Applications
Ideal for studies involving:
-
DNA/RNA synthesis disruption assays
-
Antifolate mechanism and resistance research
-
Cancer cell proliferation and cytotoxicity models
-
Combination therapies with platinums or checkpoint inhibitors
-
Pharmacokinetic/pharmacodynamic profiling
?? Research?Use Disclaimer
This product is intended strictly for laboratory research and development use only. Not for human, veterinary, clinical, diagnostic, or therapeutic applications.
其他信息
| 重量 | 1.1 公斤 |
|---|---|
| 尺寸 | 18 × 16 × 18 厘米 |
相关产品
-
Granisetron Hydrochloride Dispersible Tablets Price comparison
A 5-HT? receptor antagonist—Granisetron Hydrochloride Dispersible Tablets by Guangxi Mingjian Pharmaceutical Co., Ltd. (Guimingjian). Packaged as 1?mg tablets, 4 tablets per blister × 2 blisters per box. Approved in China (NMPA No. H20020303; product code 86905130000183). Primarily intended for clinical prevention and treatment of nausea/vomiting induced by chemotherapy, radiation, or surgery. For research use only $1.00 -
Regorafenib Tablets (Reodixin®) – 40?mg
Regorafenib (Reodixin®) is an oral multi-kinase inhibitor targeting angiogenesis, proliferation, metastasis, and tumor immunity. FDA-approved for several advanced solid tumors. Here offered as 40?mg tablets in a 28-count bottle—strictly for laboratory research use only $1.00 -
Reduced Glutathione Injection 0.6?g × 10 Vials – Ruiyang | Price comparison
Ruiyang Reduced Glutathione Injection (0.6?g per vial × 10) by Ruiyang Pharmaceutical Co., Ltd. Ideal for antioxidant, detoxification, and hepatic-protection research in metabolic and oxidative stress studies.
?? For laboratory research use only – Not for human consumption or therapeutic use. $2.00 -
Irinotecan Hydrochloride Liposome Injection (Du’EnYi®) – 10?mL:43?mg Vial
Irinotecan Hydrochloride Liposome Injection Du’EnYi® is China’s first domestically approved liposome-encapsulated irinotecan injection, equivalent to ONIVYDE®. Each 10?mL vial contains 43?mg irinotecan and is strictly for laboratory research use only—not for clinical or human application.?Please consult the staff for other purposes? $1.00
评价
目前还没有评价