Description

Polidocanol (also known as Laureth-9) is a non-ionic surfactant and sclerosing agent commonly studied in laboratory models related to vascular sclerosis, vein ablation, and cell membrane disruption.

Each ampoule contains 20mg polidocanol in 2ml (1%), supplied in a pack of 5 ampoules. This formulation is approved under China NMPA license HJ20160033, with the standard code 86979577000068.

Manufactured by Siegfried Hameln GmbH, a leading German pharmaceutical company.

Note: This product is strictly intended for laboratory research use only, not for clinical or diagnostic purposes.

Product Specifications

Mechanism of Action & Research Applications

Polidocanol acts by damaging endothelial cells and disrupting cellular membranes, leading to localized inflammation and fibrosis. In lab research, it is used to model:

• Sclerotherapy mechanisms

• Vascular inflammation

• Foam therapy comparisons

• Endothelial cytotoxicity

• Skin and cosmetic medicine studies

Its surfactant properties also make it useful in controlled membrane permeability research.

Observed Side Effects (in Lab Models)

In research models, potential side effects observed include:

• Local tissue necrosis at high concentrations

• Transient inflammation at injection sites

• Allergic-like responses in sensitive species

Handling & Safety Information

Intended Use: Laboratory research only
Personal Protective Equipment: Gloves, lab coat, eye protection
Storage: Below 25°C; avoid light and moisture
Disposal: Follow local chemical and biohazard waste regulations

Research Use Disclaimer

This product is provided exclusively for scientific and laboratory research. It is not intended for medical, diagnostic, or therapeutic use in humans or animals. Misuse may result in safety risks and regulatory consequences. Handle in accordance with institutional and national research safety protocols.