描述
Polidocanol (also known as Laureth-9) is a non-ionic surfactant and sclerosing agent commonly studied in laboratory models related to vascular sclerosis, vein ablation, and cell membrane disruption.
Each ampoule contains 20mg polidocanol in 2ml (1%), supplied in a pack of 5 ampoules. This formulation is approved under China NMPA license HJ20160033, with the standard code 86979577000068.
Manufactured by Siegfried Hameln GmbH, a leading German pharmaceutical company.
Note: This product is strictly intended for laboratory research use only, not for clinical or diagnostic purposes.
Product Specifications
Parameter | Description |
---|---|
Product Name | Polidocanol Injection (Anshuxi) |
Generic Name | Polidocanol |
CAS Number | 9002-92-0 |
Molecular Formula | C12H26O.(C2H4O)n |
Molecular Weight | Variable (dependent on ethylene oxide units) |
Concentration | 1% (20mg/2ml per ampoule) |
Formulation | Injectable Solution |
Quantity | 5 ampoules per box |
Approval Number | HJ20160033 (China NMPA) |
Product Code | 86979577000068 |
Manufacturer | Siegfried Hameln GmbH, Germany |
Storage Conditions | Store below 25°C, protected from light and moisture |
Intended Use | For laboratory research only |
Mechanism of Action & Research Applications
Polidocanol acts by damaging endothelial cells and disrupting cellular membranes, leading to localized inflammation and fibrosis. In lab research, it is used to model:
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Sclerotherapy mechanisms
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Vascular inflammation
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Foam therapy comparisons
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Endothelial cytotoxicity
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Skin and cosmetic medicine studies
Its surfactant properties also make it useful in controlled membrane permeability research.
Observed Side Effects (in Lab Models)
In research models, potential side effects observed include:
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Local tissue necrosis at high concentrations
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Transient inflammation at injection sites
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Allergic-like responses in sensitive species
Handling & Safety Information
Intended Use: Laboratory research only
Personal Protective Equipment: Gloves, lab coat, eye protection
Storage: Below 25°C; avoid light and moisture
Disposal: Follow local chemical and biohazard waste regulations
Research Use Disclaimer
This product is provided exclusively for scientific and laboratory research. It is not intended for medical, diagnostic, or therapeutic use in humans or animals. Misuse may result in safety risks and regulatory consequences. Handle in accordance with institutional and national research safety protocols.
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