Pregabalin Capsules 150?mg Factory low price wholesale
$2.00
Pregabalin is a GABA analogue and calcium channel modulator used extensively in preclinical and academic research on neuropathic pain, epilepsy, fibromyalgia, and anxiety. Supplied as 150?mg capsules in a 32-count box (8 capsules × 4 blisters), this product is manufactured by Shijiazhuang Longze Pharmaceutical Co., Ltd., and is approved in China under NMPA H20213706.?? Strictly for laboratory research use.?Please consult staff for other specifications and uses?
描述
Pregabalin is widely studied for its action as a central nervous system (CNS) depressant, especially in neuropathic pain and seizure research. As a structural analogue of ?-aminobutyric acid (GABA), it binds to the ?2? subunit of voltage-gated calcium channels and reduces neurotransmitter release. This product offers consistent bioavailability for controlled lab experiments.
Pregabalin Capsules Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Pregabalin Capsules |
| Generic Name | Pregabalin |
| CAS Number | 148553-50-8 |
| Molecular Formula | C8H17NO2 |
| Molecular Weight | 159.23?g/mol |
| Strength | 150?mg per capsule |
| Formulation | Oral hard gelatin capsules |
| Pack Size | 8 capsules × 4 blisters (32 capsules per box) |
| Approval Number | H20213706 (NMPA, China) |
| Pharmacopoeia Standard | ChP/USP/EP-compliant (varies by region) |
| Manufacturer | Shijiazhuang Longze Pharmaceutical Co., Ltd. |
| Product Code | 86979261000114 |
| Storage Conditions | Store below 25?°C; keep in original packaging |
| Intended Use | Laboratory research only |
Pregabalin Capsules Mechanism of Action
Pregabalin modulates neuronal excitability by binding to the ?2? subunit of presynaptic voltage-gated calcium channels, reducing the release of excitatory neurotransmitters like glutamate, noradrenaline, and substance P. Unlike GABA, it does not bind directly to GABA receptors or influence GABA uptake or degradation.
Pregabalin Capsules Research Applications
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Neuropathic Pain Models: Used in animal models of diabetic neuropathy, postherpetic neuralgia, and spinal cord injury.
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Epilepsy Studies: Effective in partial-onset seizure models as monotherapy or adjunct.
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Anxiety & Depression Research: Shown to modulate anxiety-like behavior and stress-induced biomarkers.
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Fibromyalgia & Chronic Pain: Studied in central sensitization and sleep disturbance models.
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CNS Drug Synergy: Often co-administered with SSRIs, gabapentin, or benzodiazepines in combinational research.
Safety Profile & Handling
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Observed Lab Effects: Drowsiness, ataxia, reduced motor coordination in rodent models.
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Handling: Use gloves and protective eyewear; minimize dust exposure during weighing.
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Stability: 36 months shelf-life under dry conditions and room temperature (?25?°C).
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Administration Note: Not injectable; oral capsule only.
Research?Use Disclaimer
This product is supplied strictly for laboratory research purposes. It is not approved for clinical, therapeutic, diagnostic, or veterinary use. Misuse may pose health risks. Purchasers must comply with local laws and institutional biosafety protocols.
其他信息
| 重量 | 1 公斤 |
|---|---|
| 尺寸 | 36 × 28 × 36 厘米 |
A1: The CAS number is 148553-50-8, used for chemical and regulatory identification.
A2: Pregabalin is ideal for pain modulation, epileptogenesis, psychiatric conditions, and calcium channel pharmacology studies.
A3: No. It is strictly intended for laboratory research use only, not for human or clinical use.
A4: Yes. Certificates of Analysis (COA) and Safety Data Sheets (SDS) are available upon request.
A5: Yes. We provide global wholesale and retail solutions for qualified research facilities and institutions.
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