Description
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Procaine Hydrochloride Injection |
| Generic Name | Procaine HCl |
| CAS Number | 51?05?8 |
| Molecular Formula | C??H??N?O?·HCl |
| Molecular Weight | ~272.8?g/mol |
| Dosage Form | Sterile aqueous injection (IV/IM/local) |
| Strength | 40?mg per 2?mL ampoule |
| Pack Size | 10 ampoules per box |
| Approval Number | H41022411 (China NMPA) |
| Product Code | 86903216000171 |
| Manufacturer | Xinxiang Changle Pharmaceutical Co., Ltd. |
| Barcode | 6946068621105 |
| Storage | Store at 2–25?°C; protect from light and moisture |
| Intended Use | Laboratory research only |
Mechanism of Action
Procaine blocks voltage-gated sodium channels, preventing neuronal depolarization and blocking nerve impulse conduction scbt.com+15ncbi.nlm.nih.gov+15pubchem.ncbi.nlm.nih.gov+15. Also inhibits calcium-induced calcium release and nicotinic acetylcholine receptors in skeletal muscle .
Research Applications & Pharmacology
Local anesthesia models: Short-term analgesia in skin, dental, or muscle research.
Antiarrhythmic and neuromodulation studies: Investigating sodium-channel blocking and cholinergic effects .
In vitro studies: Used as reference in epigenetics/cancer research due to DNA methylation inhibition .
Pharmacokinetics: Ultra-short half-life (~40–84?s, rapidly metabolized by plasma esterases) ; renal excretion.
Safety Profile & Handling
Adverse events: Possible allergic reactions (rare), CNS symptoms (dizziness, restlessness), cardiovascular changes (hypotension, bradycardia), injection-site pain .
Handling guidance: Use PPE and sterile technique; monitor for systemic toxicity; avoid in sulfonamide-based protocol due to PABA interference .
Storage: Protect from light and moisture; stable under recommended conditions.
?? Research?Use Disclaimer
This product is intended solely for laboratory research. It is not approved for diagnostic, therapeutic, clinical, or veterinary use. Improper use may pose safety risks and invalidate data.


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