Propofol Emulsion (5?×?20?mL vials) Wholesale price comparison

Propofol Emulsion (5?×?20?mL vials) Wholesale price comparison

$2.00

Propofol is a short-acting intravenous hypnotic–anesthetic agent, formulated as a medium?/long?chain lipid emulsion. This research-grade product (0.2?g in 20?mL ×?5) is intended solely for non?clinical laboratory experiments—including anesthesia models, neuropharmacology, and in vitro assays. Not approved for human, veterinary, diagnostic, or therapeutic use.?Please consult staff for other specifications and uses?

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Description

Propofol Emulsion Product Specifications

AttributeDetails
Product NamePropofol Emulsion Injection
Generic NamePropofol (2,6?diisopropylphenol)
CAS Number2078?54?8 (propofol)
Molecular FormulaC??H??O
Molecular Weight178.27?g/mol en.wikipedia.org+9accessdata.fda.gov+9en.wikipedia.org+9
Dosage FormSterile oil-in-water emulsion (IV)
Strength0.2?g / 20?mL vial
Pack Size5 vials per box
Approval NumberChina NMPA H20223914
Product Code86910137000036
ManufacturerJiangsu Yingke Biopharmaceutical Co., Ltd.
Storage ConditionsStore at 2–25?°C; protect from light; shake before use
SterilitySterile, non?pyrogenic
Intended UseLaboratory research only

Propofol Emulsion Mechanism of Action

Propofol acts as a positive allosteric modulator of GABAA_A receptors, enhancing inhibitory neurotransmission. It also exhibits mild sodium-channel and nicotinic acetylcholine receptor inhibition .


Research Applications & Pharmacology

  • Neuropharmacology & Anesthesia Models: Ideal for in vivo preclinical anesthesia induction/maintenance and monitored anesthesia care models. Commonly dosed at 2–10?mg/kg in rodents .

  • Sedation & ICU Research: Used in infusion-based sedation and propofol infusion syndrome models.

  • In Vitro Studies: Reference agent in GABAergic, neurodegeneration and pharmacokinetic assays.

  • Pharmacokinetics: Rapid onset (15–40?s), short duration (~5–10?min), high protein binding (95–99%), hepatic metabolism via glucuronidation/oxidation .


Safety Profile & Handling

  • Adverse Effects: Hypotension, respiratory depression, pain on injection, myoclonus .

  • Handling: Use aseptic technique; single?use vial; draw and administer promptly; discard within 12?hrs after opening .

  • Allergens: Contains egg lecithin and soybean oil—avoid cross?reactivity.

  • Storage: 2–25?°C, protect from light; shake until uniform before use.

Additional information

Weight1.1 kg
Dimensions18 × 16 × 18 cm

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