Description

Protirelin Acetate is a synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH), a tri-peptide tropic hormone released by the hypothalamus that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin from the anterior pituitary. TRH plays a crucial role in regulating thyroid function and has neuromodulatory effects in the central nervous system. Protirelin Acetate is utilized in laboratory research to study hypothalamic-pituitary-thyroid axis function, neuroendocrine signaling, and related physiological processes. Manufactured under GMP conditions with ?99.93% purity, it is suitable for various research applications. Strictly for laboratory research use only.

Product Specifications

Mechanism of Action & Research Applications

Protirelin Acetate functions as a synthetic analogue of TRH, binding to TRH receptors in the anterior pituitary to stimulate the release of TSH and prolactin. This action is pivotal in regulating thyroid hormone synthesis and secretion. In laboratory settings, Protirelin Acetate is employed to assess pituitary responsiveness, investigate thyroid axis disorders, and explore neuroendocrine signaling pathways. Its high purity and GMP-grade manufacturing ensure reliability and consistency in experimental outcomes. Strictly for laboratory research use only.

Side Effects (For Reference Only in Models)

While Protirelin Acetate is intended for research purposes, known side effects from clinical use of TRH include transient hypotension, nausea, and flushing. These effects are typically short-lived and occur during diagnostic procedures. Such information is valuable for interpreting experimental results and ensuring safety in laboratory environments. Strictly for laboratory research use only.

Disclaimer

This product is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Handle according to institutional safety protocols.