Description
Protirelin, also known as thyrotropin-releasing hormone (TRH), is a tripeptide hormone synthesized in the hypothalamus. It plays a crucial role in regulating thyroid function by stimulating the release of thyroid-stimulating hormone (TSH) and prolactin from the anterior pituitary gland. In addition to its endocrine functions, Protirelin has been studied for its neuromodulatory effects within the central nervous system. This synthetic analog is manufactured under GMP standards, ensuring high purity and consistency. For laboratory research use only.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Protirelin |
| CAS No. | 24305-27-9 |
| Synonyms | TRH, Thyroliberin, Thyrotropin-releasing hormone |
| Purity | ?99.98% |
| Molecular Formula | C??H??N?O? |
| Molecular Weight | 362.39 Da |
| Appearance | White to off-white powder |
| Solubility | Soluble in water |
| Storage Conditions | Store at 2–8°C, protected from light |
| Manufacturing Standard | GMP-compliant |
| Intended Use | Laboratory research only |
Mechanism of Action & Research Applications
Protirelin functions by binding to specific receptors in the anterior pituitary gland, leading to the release of TSH and prolactin. This action is pivotal in regulating thyroid hormone synthesis and secretion. Beyond its role in endocrine regulation, Protirelin has been investigated for its potential neuroprotective effects and its involvement in central thermoregulation. Laboratory studies utilize Protirelin to explore its impact on thyroid function, neuroendocrine signaling pathways, and its broader physiological effects within the central nervous system. For laboratory research use only.
Side Effects (For Reference Only in Models)
In laboratory models, Protirelin administration may lead to transient hypotension, flushing, and headache. These effects are typically mild and reversible. It is essential to consider these potential outcomes when designing experiments involving Protirelin. For laboratory research use only.
Disclaimer
This product is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Handling should follow institutional safety protocols.


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