Description
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Pyrogallol Injection (Betet/Temito®) |
| Generic Name | Pyrogallol (1,2,3?trihydroxybenzene) |
| CAS Number | 87?66?1? |
| Molecular Formula | C?H?O? |
| Molecular Weight | ~126.11?g/mol |
| Dosage Form | Solution for injection (sterile) in lyophilized or solution format |
| Strength | 10?mg/mL (total 40?mg per 4?mL vial) |
| Pack Size | 5 vials per box |
| Approval Number | H20233230 (NMPA, China) |
| Product Code | 86902013001442 |
| Manufacturer | Chengdu Betet Pharmaceutical Co., Ltd. |
| Barcode | 6923528100356 |
| Storage | Store at 2–8?°C, protect from light |
| Intended Use | Laboratory research use only |
Mechanism of Action
Pyrogallol is a pro-oxidant phenolic compound that generates reactive oxygen species (ROS) and induces oxidative stress. It causes DNA damage, lipid peroxidation, and alters cellular redox status, making it useful as a tool in immunosuppression and oxidative stress models?sigmaaldrich.com+10sciencedirect.com+10adipogen.com+10.
Research Applications & Pharmacology
Oxidative stress models: Induces ROS and lipid peroxidation; used in in vivo and in vitro studies to assess antioxidant and immunomodulatory agents (e.g., effective immunosuppression at 50?mg/kg in rats)?.
Pulmonary research: Intravenous or inhalational pyrogallol can modulate airway and vascular tone in lung injury studies?.
Cancer research: Exhibits anti-proliferative activity in cancer cell lines (e.g., A549, ovarian carcinoma, Calu?6), inducing apoptosis via oxidative stress pathways .
Safety Profile & Handling
Adverse Effects (preclinical context):
Cytotoxicity at ?50?mg/kg in rodents
Potential oxidative tissue damage and genotoxicity?
Handling Guidelines:
Use PPE (gloves, goggles) and biosafety cabinets
Reconstitute with sterile solvent; monitor pH and stability
Store vials refrigerated
Dispose of waste as chemical and oxidative hazard per local regulations
Avoid light exposure; may darken on oxidation?
?? Research?Use Disclaimer
This product is intended solely for laboratory research. It is not approved for therapeutic, diagnostic, clinical, or veterinary applications. Misuse may pose health hazards and compromise scientific outcomes.


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