Description
Rasagiline is widely studied for its dopaminergic neuroprotection and Parkinson’s disease (PD) mechanisms. It inhibits the MAO-B enzyme, reducing dopamine breakdown in the brain. This model compound is critical for exploring dopaminergic neurodegeneration, oxidative stress, and neurotransmitter modulation.
Rasagiline Mesylate Tablets Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Rasagiline Mesylate Tablets |
| Generic Name | Rasagiline (as mesylate) |
| CAS Number | 136236-51-6 |
| Molecular Formula | C12H13N•CH4O3S |
| Molecular Weight | 267.33?g/mol |
| Formulation | Oral film-coated tablets |
| Strength | 1?mg per tablet |
| Packaging | 28 tablets per box |
| Dosage Form | Tablets |
| Approval Number | H20243784 (NMPA China) |
| Manufacturer | Zhejiang Huahai Pharmaceutical Co., Ltd. |
| Product Code | 86904647001584 |
| Storage | Store in a cool, dry place at room temperature |
| Intended Use | For laboratory research use only |
Rasagiline Mesylate Tablets Mechanism of Action
Rasagiline selectively and irreversibly inhibits monoamine oxidase-B (MAO?B), the enzyme responsible for the breakdown of dopamine in the brain. This increases synaptic dopamine availability and reduces oxidative stress. It is widely used in Parkinson’s disease (PD) research and neuroprotection studies.
Research Applications
Parkinson’s Disease Modeling: Used in in-vitro and in-vivo models simulating dopaminergic neuron degeneration.
Neuroprotection Studies: Shows antioxidant and anti-apoptotic effects.
CNS Neurotransmitter Studies: Useful for analyzing dopamine, norepinephrine, and serotonin metabolism.
Combination Therapy Exploration: Studied with levodopa or dopamine agonists.
Oxidative Stress Pathways: Relevant to mitochondrial dysfunction and aging-related studies.
Safety Profile & Handling
Lab Observations: Dose-dependent behavioral effects in animal models; no significant off-target toxicity at low research doses.
Handling Instructions: Use gloves, protective gear; store securely away from incompatible materials.
Stability: Stable for up to 24 months when stored at room temperature in original packaging.
Reconstitution: Not required; oral tablet formulation.
Core Keywords
Rasagiline Mesylate, Rasagiline Tablets, CAS 136236-51-6, MAO-B inhibitor, Parkinson’s disease research, dopaminergic neuroprotection, CNS drug studies, Huahai Pharmaceutical, lab-grade Rasagiline, wholesale Rasagiline tablets
Research-Use Disclaimer
This product is intended strictly for laboratory research use only. It is not for use in humans or animals. Misuse may result in health hazards. All buyers must comply with local regulatory and biosafety requirements.


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