描述
Recombinant Human Interferon ?1b Product Specifications
Attribute | Details |
---|---|
Product Name | Recombinant Human Interferon ?1b Injection (Yundesu®) |
Generic Name | Interferon ?1b, recombinant |
CAS Number | 175061?16?4 |
Molecular Formula | 166 amino acid polypeptide (no glycosylation) |
Molecular Weight | ~19.4?kDa |
Dosage Form | Lyophilized powder for injection |
Strength | 30??g per vial |
Pack Size | 1 vial per box |
Approval Number | S19990034 (China NMPA) |
Product Code | 86900115000011 |
Manufacturer | Beijing Sanyuan Gene Pharmaceutical Co., Ltd. |
Barcode | 6924520520005 |
Storage | Store at –20?°C; avoid freeze–thaw cycles |
Intended Use | Laboratory research only |
Recombinant Human Interferon ?1b Mechanism of Action
Recombinant IFN-?1b is a type I interferon produced in E. coli that binds the IFNAR receptor, activating the JAK?STAT pathway. This triggers transcription of antiviral and immunomodulatory genes, leading to inhibition of viral replication, activation of NK cells, and suppression of tumor cell proliferation.
Research Applications & Pharmacology
-
Antiviral models: Effective in SARS-CoV?2, RSV, and chronic Hepatitis B research
-
Oncology immunostimulant: Used in studies of tumor immunotherapy and hematologic malignancies
synapse.patsnap.com+11frontiersin.org+11cancer.gov+11 -
Mechanistic assays: Ideal for gene expression, PK/PD, and signal pathway studies
-
Pharmacokinetics: Polypeptide, dosage/timing vary; use sterile preparation per protocol
Safety Profile & Handling
Preclinical observations:
-
Possible transient fever, malaise, injection-site reactions
-
Typically low toxicity in animal models at researched dosages
Lab precautions:
-
Use full sterile technique (PBS reconstitution)
-
Use personal protective equipment (PPE) when handling vials
-
Monitor immune markers or body temperature in animal studies
-
Treat as bioactive protein; avoid inhalation, ingestion, or skin contact
?? Research?Use Disclaimer
This product is intended exclusively for laboratory research use. It is not approved for diagnostic, clinical, therapeutic, or veterinary use. Misuse may lead to serious health and safety risks, and compromise research integrity.
评价
目前还没有评价