描述
Regorafenib Tablets Product Specifications
Attribute | Details |
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Product Name | Regorafenib Tablets (Reodixin®) |
Strength | 40?mg per tablet |
Quantity | 28 tablets per bottle |
Dosage Form | Oral film-coated tablet |
Approval No. | China NMPA H20243057 |
Product Code | 86900647000343 |
Manufacturer | Shanghai Chuannuo Pharmaceutical Co., Ltd. |
Intended Use | Laboratory research use only—Not for human or veterinary use |
Overview & Mechanism
Regorafenib is a potent multi-kinase inhibitor that targets RTKs critical to tumor growth: VEGFR1/2/3, TIE2, PDGFR, FGFR, KIT, RET, RAF1, BRAF, and CSF1R. It suppresses angiogenesis, proliferation, metastasis, and modulates the tumor immune microenvironment sciencedirect.comoncologynewscentral.com+5stivarga.com+5stivargahcp.com+5de.wikipedia.org+2pmc.ncbi.nlm.nih.gov+2stivargahcp.com+2.
Research & Clinical Background
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FDA-approved for metastatic colorectal cancer, GIST, and hepatocellular carcinoma
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Shown to extend median overall survival in metastatic colorectal cancer (CORRECT, CONCUR trials) by ~1.4–2.5 months
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Demonstrates broad signaling pathway inhibition, including anti-angiogenic and immunomodulatory effects
Research Applications
Ideal for use in:
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Angiogenesis and TME modeling
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Kinase signaling pathway assays
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Drug resistance and combination studies
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Metastasis and proliferation models
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Pharmacodynamic and bioactivity profiling
?? Research-Use Disclaimer
This product is provided strictly for laboratory research and development use only.
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