Retatrutide revolutionizes obesity, diabetes and fatty liver freeze-dried powder wholesale

描述

In the realm of metabolic health and weight management, Retatrutide has emerged as a groundbreaking peptide with unparalleled potential. As a triple agonist of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R), Retatrutide is redefining the approach to treating obesity, type 2 diabetes, and fatty liver disease. Manufactured under GMP (Good Manufacturing Practice) standards with a purity of 99.5%, Retatrutide is available in 10mg, 12mg, and 25mg formulations, making it a versatile and reliable choice for researchers and healthcare professionals worldwide.

What is Retatrutide?

Retatrutide is a 39-amino acid single peptide conjugated to a C20 fatty diacid moiety at position 17. Its unique structure includes three non-coded amino acids: Aib2 (?-amino isobutyric acid) at positions 2 and 20, and ?MeL13 (?-methyl-L-leucine) at position 20. These modifications enhance its stability against Dipeptidyl Peptidase 4 (DPP4) cleavage and contribute to its potent activity at the GIPR, GCGR, and GLP-1R receptors.

Key Features of Retatrutide:

• Triple-Action Mechanism: Targets GLP-1, GIP, and GCGR receptors for comprehensive metabolic benefits.
• High Purity: Manufactured with 99.5% purity under GMP standards.
• Versatile Applications: Ideal for research on obesity, type 2 diabetes, and fatty liver disease.
• Customizable Dosages: Available in 10mg, 12mg, and 25mg formulations.

How Does Retatrutide Work?

Retatrutide’s triple-action mechanism makes it a powerful tool for metabolic research and therapeutic development:

1. Stimulates Insulin Release

By activating the GLP-1 receptor, Retatrutide enhances glucose-dependent insulin secretion, helping to regulate blood sugar levels in individuals with type 2 diabetes.

2. Suppresses Appetite

Retatrutide’s action on the GIP receptor promotes satiety and reduces food intake, making it an effective option for weight management and obesity research.

3. Promotes Fat Breakdown

Through its activity at the GCGR receptor, Retatrutide stimulates lipolysis (fat breakdown) and energy expenditure, supporting weight loss and metabolic health.

Applications of Retatrutide

Retatrutide is a versatile peptide with a wide range of applications in metabolic and obesity-related research:

1. Obesity and Overweight Conditions

Retatrutide has shown significant promise in promoting weight loss and improving body composition in clinical trials. Its ability to suppress appetite and enhance fat metabolism makes it a valuable tool for obesity research.

2. Type 2 Diabetes

By improving insulin secretion and sensitivity, Retatrutide helps regulate blood sugar levels, making it a potential therapeutic option for type 2 diabetes management.

3. Fatty Liver Disease

Retatrutide’s ability to promote fat breakdown and improve metabolic health makes it a promising candidate for research on non-alcoholic fatty liver disease (NAFLD).

4. Cardiovascular Health

Retatrutide has been studied for its potential to reduce cardiovascular risk factors associated with obesity and diabetes, such as hypertension and dyslipidemia.

Clinical Trials and Research

Retatrutide is backed by extensive clinical research, with numerous trials conducted by Eli Lilly and Company. These studies highlight its efficacy and safety in addressing obesity, type 2 diabetes, and related conditions. Key clinical trials include:

• NCT04881760: Phase 2 study on obesity and overweight conditions.
• NCT04867785: Phase 2 study on type 2 diabetes.
• NCT05929079: Phase 3 study on obesity, type 2 diabetes, and obstructive sleep apnea.
• NCT05936151: Phase 2 study on overweight/obesity, chronic kidney disease (CKD), and type 2 diabetes.

These trials demonstrate Retatrutide’s potential to address multiple metabolic and weight-related conditions, making it a valuable asset for researchers and healthcare providers.

Product Specifications

• Molecular Weight: 4731.33 (free base)
• Formula: C221H342N46O68.xC2HF3O2
• Appearance: Solid, white to off-white powder
• Sequence: Tyr-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{?-Me-Leu}-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
• Purity: 99.5%
• Dosages: 10mg, 12mg, 25mg
• Storage:
  • Powder: Store at -80°C for up to 2 years or -20°C for up to 1 year.
  • Sealed storage, away from moisture.
  •                                      

Why Choose Our Retatrutide?

1. GMP-Certified Manufacturing

Our Retatrutide is produced under strict GMP standards, ensuring the highest quality and consistency for research purposes.

2. High Purity and Reliability

With a purity of 99.5%, our Retatrutide is rigorously tested to meet international quality standards, providing reliable results for your research.

3. Customizable Solutions

We offer flexible packaging and dosage options to meet your specific research needs. Whether you require small quantities for preliminary studies or bulk orders for large-scale research, we’ve got you covered.

4. Global Shipping and Support

We provide fast and secure shipping to researchers worldwide, along with dedicated customer support to assist you at every step.

Frequently Asked Questions (FAQ)

Q1: What is the purity of Retatrutide?

• Our Retatrutide is manufactured with a purity of 99.5%, ensuring optimal quality for research purposes.

Q2: How is Retatrutide shipped and stored?

• Retatrutide is shipped at room temperature and should be stored at -80°C for long-term preservation or -20°C for short-term use. Keep it sealed and away from moisture.

Q3: Can I request custom packaging or dosages?

• Yes, we offer customizable packaging and dosage options to meet your specific research requirements.

Q4: Are there any clinical trials supporting Retatrutide’s efficacy?

• Yes, Retatrutide has been extensively studied in clinical trials, including Phase 2 and Phase 3 studies conducted by Eli Lilly and Company.

Q5: How can I place an order?

• Contact us via email or our website to discuss your requirements. We will provide a quotation and guide you through the ordering process.