Description
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Ropivacaine Hydrochloride Injection |
| Generic Name | Ropivacaine (S?enantiomer, HCl salt) |
| CAS Number | 84057?95?4 |
| Molecular Formula | C??H??N?O·HCl |
| Molecular Weight | ~274.4?g/mol |
| Dosage Form | Sterile aqueous solution for IV/IM/perineural injection |
| Strength | 100?mg per 10?mL vial (1%) |
| Pack Size | 1 vial per box |
| Approval Number | H20233822 (China NMPA) |
| Product Code | 86901012000784 |
| Manufacturer | Chengdu Baiyu Pharmaceutical Co., Ltd. |
| Barcode | 6947954800208 |
| Storage | Store at 2–25?°C; protect from light |
| Intended Use | Laboratory research only |
Mechanism of Action
Ropivacaine blocks voltage-gated sodium channels in neuronal membranes, inhibiting nerve impulse conduction. As a pure S-enantiomer, it provides effective sensory block with less motor block and reduced cardiotoxicity compared to bupivacaine meritpharm.com+15researchgate.net+15go.gale.com+15.
Research Applications & Pharmacology
Regional anesthesia models: Used in peripheral nerve block, epidural, spinal anesthesia, and surgical infiltration ncbi.nlm.nih.gov+3medicines.org.uk+3dailymed.nlm.nih.gov+3.
Pharmacokinetics:
Onset: ~10–45 minutes depending on route
Duration: up to 6–8 hours
Half-life: 1.6–6 hours
Metabolized in the liver (CYP1A2) and ?86% excreted renally en.wikipedia.org+3en.wikipedia.org+3zh.wikipedia.org+3
Safety Profile & Handling
Side effects: Minimal motor blockade; low risk of CNS symptoms (dizziness, tinnitus) or cardiovascular effects (hypotension, arrhythmia) .
Handling tips:
Administer under aseptic conditions.
Monitor for signs of systemic toxicity—stop if noted.
Have lipid emulsion therapy ready for overdose .
?? Research?Use Disclaimer
This product is intended solely for laboratory research. It is not approved for clinical, therapeutic, diagnostic, or veterinary applications. Misuse may pose health risks and compromise data integrity.


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