Description
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Ropivacaine Mesylate Injection |
| Generic Name | Ropivacaine (S?enantiomer) |
| CAS Number | 854056?07?8 |
| Molecular Formula | C??H??N?O?S |
| Molecular Weight | ~274.4?g/mol |
| Dosage Form | Aqueous solution for IV/IM injection |
| Strength | 4?mg per ampoule |
| Pack Size | 5 ampoules per box |
| Approval Number | H20060477 (China NMPA) |
| Product Code | 86902499000120 |
| Manufacturer | Xi’an Hanfeng Pharmaceutical Co., Ltd. |
| Barcode | 6947954800208 |
| Storage | Store at 2–25?°C; protect from light |
| Intended Use | Laboratory research only |
Mechanism of Action
Ropivacaine blocks voltage-gated sodium channels in nerve fibers, inhibiting nerve impulse conduction. It is less lipophilic than bupivacaine, resulting in more sensory-selective blockade and reduced risk of cardiotoxicity and CNS side effects. Its reversible inhibition allows prolonged anesthesia with a favorable motor-sensory profile .
Research Applications & Pharmacology
Regional anesthesia models: ideal for peripheral nerve blocks, epidural anesthesia, surgical anesthesia, and acute pain relief protocols patents.google.com.
Pharmacokinetics:
Onset: 10–45?min depending on application
Duration: 90?min–8?hrs
Half-life: 1.6–6?hr
Extensive hepatic metabolism; renal excretion (~86%) cphi-online.com+15accessdata.fda.gov+15sciencedirect.com+15researchgate.net+8en.wikipedia.org+8zh.wikipedia.org+8
Safety Profile & Handling
Observed effects: Minimal motor blockade, low histamine release, rare CNS symptoms (e.g., dizziness, tinnitus), and occasional cardiovascular effects (hypotension, arrhythmia).
Handling recommendations: Use PPE and sterile technique for IV/IM administration. Monitor for signs of systemic toxicity. In case of overdose, lipid emulsion therapy is advised .
?? Research?Use Disclaimer
This product is for laboratory research only. It is not approved for therapeutic, diagnostic, clinical, or veterinary use. Improper use may pose serious safety risks and compromise research integrity.


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